Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells
about
Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cellsHoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cellsDifferential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1HOXA9 regulates miR-155 in hematopoietic cellsUnique molecular characteristics of pediatric myxopapillary ependymomaConstitutively active SHP2 cooperates with HoxA10 overexpression to induce acute myeloid leukemiaThe homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesisHOX genes in human lung: altered expression in primary pulmonary hypertension and emphysemaHox expression in AML identifies a distinct subset of patients with intermediate cytogeneticsSurvival regulation of leukemia stem cellsSALL4 is a key transcription regulator in normal human hematopoiesisNUP98 dysregulation in myeloid leukemogenesisA SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesisHigh levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming eventEvidence that the Pim1 kinase gene is a direct target of HOXA9Chromosomal minimal critical regions in therapy-related leukemia appear different from those of de novo leukemia by high-resolution aCGH.Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9Integrative meta-analysis of differential gene expression in acute myeloid leukemiaHoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid LeukemiaMeis1 regulates proliferation of non-small-cell lung cancer cells.Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motifMeis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia.Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression.Expression profiling of single mammalian cells--small is beautifulIdentification of E74-like factor 1 (ELF1) as a transcriptional regulator of the Hox cofactor MEIS1.MLL fusion partners AF4 and AF9 interact at subnuclear foci.HoxA10 regulates transcription of the gene encoding transforming growth factor beta2 (TGFbeta2) in myeloid cells.Regulation of CDX4 gene transcription by HoxA9, HoxA10, the Mll-Ell oncogene and Shp2 during leukemogenesisHuman hematopoietic lineage commitment.HoxA10 influences protein ubiquitination by activating transcription of ARIH2, the gene encoding Triad1.Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations.The deficiency of tumor suppressor prep1 accelerates the onset of meis1- hoxa9 leukemogenesisE2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice.NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insightsRetrovirus-Mediated Expression of E2A-PBX1 Blocks Lymphoid Fate but Permits Retention of Myeloid Potential in Early Hematopoietic Progenitors.Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus.Hypoxic metabolism in human hematopoietic stem cells.MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyondHoxA10 protein regulates transcription of gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells.
P2860
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P2860
Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@ast
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@en
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@nl
type
label
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@ast
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@en
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@nl
prefLabel
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@ast
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@en
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@nl
P2093
P6179
P3181
P1433
P1476
Expression of HOX genes, HOX c ...... rmal human hematopoietic cells
@en
P2093
H J Sutherland
R K Humphries
P304
P3181
P356
10.1038/SJ.LEU.2401410
10.1038/SJ/LEU/2401410
P407
P577
1999-05-01T00:00:00Z
P6179
1011239909
1056650394