CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways
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Therapeutic potential for novel drugs targeting the type 1 cholecystokinin receptorPKD signaling and pancreatitisProtein kinase D enzymes: novel kinase targets in pancreatic cancerInsights into bombesin receptors and ligands: Highlighting recent advancesBombesin receptor subtype 3 as a potential target for obesity and diabetes.Gastrointestinal hormones/neurotransmitters and growth factors can activate P21 activated kinase 2 in pancreatic acinar cells by novel mechanismsPharmacology of putative selective hBRS-3 receptor agonists for human bombesin receptors (BnR): affinities, potencies and selectivity in multiple native and BnR transfected cells.The novel protein kinase C isoforms -delta and -epsilon modulate caerulein-induced zymogen activation in pancreatic acinar cells.Elucidation of the roles of the Src kinases in pancreatic acinar cell signalingA novel protein kinase D inhibitor attenuates early events of experimental pancreatitis in isolated rat aciniLysophosphatidylcholine activates a novel PKD2-mediated signaling pathway that controls monocyte migrationPKCθ activation in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters and growth factors is needed for stimulation of numerous important cellular signaling cascades.Cholinergic signaling inhibits oxalate transport by human intestinal T84 cells.The Src kinase Yes is activated in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters, but not pancreatic growth factors, which stimulate its association with numerous other signaling moleculesMorphologic characterization of early ligation-induced acute pancreatitis in ratsHistamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells.The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis eventsProtein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cellsExtracellular nucleotides inhibit oxalate transport by human intestinal Caco-2-BBe cells through PKC-δ activation.PKD3 is the predominant protein kinase D isoform in mouse exocrine pancreas and promotes hormone-induced amylase secretionPancreatic acinar cell nuclear factor κB activation because of bile acid exposure is dependent on calcineurin.Gastrointestinal growth factors and hormones have divergent effects on Akt activation.Comparative pharmacology of bombesin receptor subtype-3, nonpeptide agonist MK-5046, a universal peptide agonist, and peptide antagonist Bantag-1 for human bombesin receptorsProtein kinase C delta-mediated processes in cholecystokinin-8-stimulated pancreatic aciniProtein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2.Molecular mechanisms of pancreatic injury.Pathogenic mechanisms of acute pancreatitis.CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production.Protein kinase d regulates cell death pathways in experimental pancreatitis.Regulation of PKD1-mediated Golgi to cell surface trafficking by Gαq subunits.Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis.Protein kinase C isoforms in the normal pancreas and in pancreatic disease.The effect of electroacupuncture on insulin-like growth factor-I and oxidative stress in an animal model of renal failure-induced hypertension.FGF21 Is an Exocrine Pancreas Secretagogue.
P2860
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P2860
CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
CCK causes PKD1 activation in ...... a and PKC-independent pathways
@ast
CCK causes PKD1 activation in ...... a and PKC-independent pathways
@en
type
label
CCK causes PKD1 activation in ...... a and PKC-independent pathways
@ast
CCK causes PKD1 activation in ...... a and PKC-independent pathways
@en
prefLabel
CCK causes PKD1 activation in ...... a and PKC-independent pathways
@ast
CCK causes PKD1 activation in ...... a and PKC-independent pathways
@en
P2093
P2860
P1476
CCK causes PKD1 activation in ...... a and PKC-independent pathways
@en
P2093
Andrea Pace
Jose A Tapia
K Martin Hoffmann
Marc J Berna
Michelle Thill
Robert T Jensen
Samuel A Mantey
P2860
P304
P356
10.1016/J.BBAMCR.2006.12.008
P407
P577
2006-12-24T00:00:00Z