Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
about
The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stabilityFbxw7 regulates lipid metabolism and cell fate decisions in the mouse liverInhibition of c-Myc activity by ribosomal protein L11myc maintains embryonic stem cell pluripotency and self-renewalKruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesisc-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XLGenomic targets of the human c-Myc proteinGlobal transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cellsEfficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectorsEmerging Technologies to Create Inducible and Genetically Defined Porcine Cancer ModelsReduced expression of MYC increases longevity and enhances healthspan.Redirection of B cell responsiveness by transforming growth factor beta receptorN-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiationc-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cellsC-myc as a modulator of renal stem/progenitor cell populationStress response gene ATF3 is a target of c-myc in serum-induced cell proliferationA functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolismc-Myc-deficient B lymphocytes are resistant to spontaneous and induced cell deathDeletion of Mnt leads to disrupted cell cycle control and tumorigenesisThe Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineagec-Rel deficiency increases caspase-4 expression and leads to ER stress and necrosis in EBV-transformed cellsDeciphering c-MYC-regulated genes in two distinct tissues.Characterization of parameters required for effective use of tamoxifen-regulated recombination.A Myc-regulated transcriptional network controls B-cell fate in response to BCR triggering.Myc suppression of Nfkb2 accelerates lymphomagenesis.MYC and the control of DNA replication.Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complexMyc in model organisms: a view from the flyroom.Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice.c-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liverMcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia.Growth inhibition and DNA damage induced by Cre recombinase in mammalian cellsSelective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain.Disentangling the MYC web.The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centersCell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation.c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells.Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expressionHuman c-Myc isoforms differentially regulate cell growth and apoptosis in Drosophila melanogaster.
P2860
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P2860
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@ast
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@en
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@nl
type
label
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@ast
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@en
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@nl
prefLabel
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@ast
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@en
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@nl
P2093
P3181
P1433
P1476
Analysis of C-MYC function in normal cells via conditional gene-targeted mutation
@en
P2093
I M de Alboran
L Davidson
R A DePinho
R C O'Hagan
P3181
P356
10.1016/S1074-7613(01)00088-7
P407
P577
2001-01-01T00:00:00Z