BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
about
p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XLThe growth-promoting activity of the Bad protein in chicken embryo fibroblasts requires binding to protein 14-3-3Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic functionProtection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signalingParkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosisDAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagyInvolvement of 14-3-3 Proteins in Regulating Tumor Progression of Hepatocellular CarcinomaBcl2 Family Functions as Signaling Target in Nicotine-/NNK-Induced Survival of Human Lung Cancer Cells.Lipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathwayPhosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowthBAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest14-3-3 proteins--an updateSurvival function of protein kinase C{iota} as a novel nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-activated bad kinaseInvolvement of DNase gamma in apoptosis associated with myogenic differentiation of C2C12 cellsIdentification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activityInterleukin-18 delays neutrophil apoptosis following alcohol intoxication and burn injuryUrocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery: Role of EPAC2 and ERK1/2Dual role of proapoptotic BAD in insulin secretion and beta cell survivalp70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BADPim3 negatively regulates glucose-stimulated insulin secretionProtein tyrosine phosphatase interacting protein 51--a jack-of-all-trades protein.Interdependence of Bad and Puma during ionizing-radiation-induced apoptosis.BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis.The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Mesenchymal stem cells secrete multiple cytokines that promote angiogenesis and have contrasting effects on chemotaxis and apoptosis.14-3-3beta binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function.14-3-3 proteins: key regulators of cell division, signalling and apoptosis.Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cellsSorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma.Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase.Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt.BAD dephosphorylation and decreased expression of MCL-1 induce rapid apoptosis in prostate cancer cells.The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BADInducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia.A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic responseProteomic analysis of hypoxia/ischemia-induced alteration of cortical development and dopamine neurotransmission in neonatal rat.p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest.
P2860
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P2860
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@ast
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@en
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@nl
type
label
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@ast
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@en
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@nl
prefLabel
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@ast
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@en
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@nl
P2093
P2860
P3181
P356
P1476
BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M004199200
P407
P577
2000-08-18T00:00:00Z