c-Cbl is a critical modulator of the Ron tyrosine kinase receptor - Wikidata - awgldk - TriplyDB

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

http://www.wikidata.org/entity/Q28178593

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Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction The carboxyl terminus of VEGFR-2 is required for PKC-mediated down-regulation Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase.RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.Short-Form Ron Promotes Spontaneous Breast Cancer Metastasis through Interaction with Phosphoinositide 3-Kinase.Identification of the Mind Bomb1 Interaction Domain in Zebrafish DeltaD.c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses.Oncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers.Peritumoral Cbl is a strong independent prognostic marker after curative resection of hepatocellular carcinoma Endocytosis of receptor tyrosine kinases HIV-1 Tat mediates degradation of RON receptor tyrosine kinase, a regulator of inflammation.Significance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160 Degradation of activated protein kinases by ubiquitination.Cbl-family proteins as regulators of cytoskeleton-dependent phenomena.Molecular mechanisms of SH2- and PTB-domain-containing proteins in receptor tyrosine kinase signaling.Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain.Regulation of RON tyrosine kinase-mediated invasion of breast cancer cells.A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation.Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.Development of an LC-MALDI method for the analysis of protein complexes.Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt.RON Signaling Is a Key Mediator of Tumor Progression in Many Human Cancers.

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P2860

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

http://www.wikidata.org/entity/Q28178593

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@ast

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@en

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

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type

label

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@ast

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@en

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

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prefLabel

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@ast

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@en

c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@nl

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c-Cbl is a critical modulator of the Ron tyrosine kinase receptor

@en

P2093

Chanan Rubin

http://www.w3.org/2001/XMLSchema#string

Lorenza Penengo

http://www.w3.org/2001/XMLSchema#string

Yosef Yarden

http://www.w3.org/2001/XMLSchema#string

P2860

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells

Cbl: many adaptations to regulate protein tyrosine kinases.

Invasive growth: from development to metastasis

Overexpression and activation of the RON receptor tyrosine kinase in a panel of human colorectal carcinoma cell lines.

Macrophage stimulating protein-induced epithelial cell adhesion is mediated by a PI3-K-dependent, but FAK-independent mechanism.

Activation of the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase by macrophage-stimulating protein results in the induction of arginase activity in murine peritoneal macrophages.

P2888

P304

3669-79

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scholarly article

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10.1038/SJ.ONC.1206585

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24

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22

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Giovanni Gaudino

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2003-06-12T00:00:00Z

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10712599

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1031393063

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12802274

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