Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. - Wikidata - awgldk - TriplyDB

Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor.

Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor.

http://www.wikidata.org/entity/Q33863959

about

Microspherule protein 2 associates with ASK1 and acts as a negative regulator of stress-induced ASK1 activation PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex Microspherule protein 1, Mi-2beta, and RET finger protein associate in the nucleolus and up-regulate ribosomal gene transcription Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival.MCRS2 represses the transactivation activities of Nrf1.PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma.Phosphatase and tensin homologue growth suppression without phosphatase Functional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2.Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control MCRS1 overexpression, which is specifically inhibited by miR-129*, promotes the epithelial-mesenchymal transition and metastasis in non-small cell lung cancer.Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification.PTEN: Multiple Functions in Human Malignant Tumors NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN.PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formation Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)RNAi-mediated inhibition of MSP58 decreases tumour growth, migration and invasion in a human glioma cell line.58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway.The candidate oncogene (MCRS1) promotes the growth of human lung cancer cells via the miR-155-Rb1 pathway.Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing.Expression of MSP58 in human colorectal cancer and its correlation with prognosis.The novel interaction between microspherule protein Msp58 and ubiquitin E3 ligase EDD regulates cell cycle progression.MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment.Portrait of PTEN: messages from mutant mice.Selection by drug resistance proteins located in the mitochondria of mammalian cells.PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling PTEN in brain tumors.Inhibition of the phosphatase PTEN protects mice against oleic acid-induced acute lung injury PTEN and the PI3-kinase pathway in cancer Mapping signals that are important for nuclear and nucleolar localization in MCRS2.PRL-3 phosphatase and cancer metastasis.Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.PTEN-Associated Complexes: An Overview.PTEN function: the long and the short of it.PTEN deletion leads to up-regulation of a secreted growth factor pleiotrophin.PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity.Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway.

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P2860

Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor.

http://www.wikidata.org/entity/Q33863959

description

2005 nî lūn-bûn

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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2005年の論文

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Cellular transformation by the ...... ith the PTEN tumor suppressor.

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Cellular transformation by the ...... ith the PTEN tumor suppressor.

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Cellular transformation by the ...... ith the PTEN tumor suppressor.

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Cellular transformation by the ...... ith the PTEN tumor suppressor.

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Cellular transformation by the ...... ith the PTEN tumor suppressor.

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Cellular transformation by the ...... ith the PTEN tumor suppressor.

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Proceedings of the National Academy of Sciences of the United States of America

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Cellular transformation by the ...... ith the PTEN tumor suppressor.

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P2093

Koichi Okumura

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Mujun Zhao

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Ronald A Depinho

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Webster K Cavenee

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P2860

Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells.

Phosphorylation of the PTEN tail regulates protein stability and function

Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration

Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

PTEN and myotubularin: novel phosphoinositide phosphatases.

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

PTEN: one gene, many syndromes

Direct identification of PTEN phosphorylation sites

Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation

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2703-2706

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Frank B Furnari

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8071002

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