Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs
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Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complexPTEN inhibits BMI1 function independently of its phosphatase activityThe ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localizationThe PTEN tumor suppressor gene and its role in lymphoma pathogenesisFocus on PTEN RegulationBalancing Proliferation and Connectivity in PTEN-associated Autism Spectrum DisorderPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsSubcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersTherapeutic targeting of cancers with loss of PTEN function.PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppressionA functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activityInteractions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapySpecific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cellsAMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressorAcid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells.Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survivalLung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN.A unified nomenclature and amino acid numbering for human PTEN.ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cellsRegulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN.Fine-Tuning of Pten Localization and Phosphatase Activity Is Essential for Zebrafish Angiogenesis.Expression of NF-κB and PTEN in primary epithelial ovarian carcinoma and the correlation with chemoresistance.Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance.ATP modulates PTEN subcellular localization in multiple cancer cell lines.Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function.PTEN and the PI3-kinase pathway in cancerAnalysis of PTEN complex assembly and identification of heterogeneous nuclear ribonucleoprotein C as a component of the PTEN-associated complex.Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer.PTEN in DNA damage repair.Study of PTEN subcellular localization.The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.CDX2 inhibits invasion and migration of gastric cancer cells by phosphatase and tensin homologue deleted from chromosome 10/Akt signaling pathway.Semaphorin 3A upregulates FOXO 3a-dependent MelCAM expression leading to attenuation of breast tumor growth and angiogenesis.Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN.Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway.Cellular localization of MAGI-1 caspase cleavage products and their role in apoptosis.A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth.A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development.Chromatin PTEN is involved in DNA damage response partly through regulating Rad52 sumoylation.
P2860
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P2860
Nuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifs
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im September 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/09/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/09/01)
@nl
наукова стаття, опублікована у вересні 2006
@uk
مقالة علمية (نشرت في سبتمبر 2006)
@ar
name
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@ast
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@en
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@nl
type
label
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@ast
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@en
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@nl
prefLabel
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@ast
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@en
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@nl
P2093
P2860
P3181
P356
P1476
Nuclear localization of PTEN b ...... tiple nuclear exclusion motifs
@en
P2093
Amparo Andrés-Pons
Anabel Gil
Elena Fernández
Javier Cervera
Josema Torres
Miguel Valiente
Rafael Pulido
P2860
P304
P3181
P356
10.1091/MBC.E06-05-0380
P577
2006-09-01T00:00:00Z