Regulation of HDM2 activity by the ribosomal protein L11
about
PML regulates p53 stability by sequestering Mdm2 to the nucleolusThe balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cellsRegulation of p53 stability and function by the deubiquitinating enzyme USP42Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitinationInterdependence of Pes1, Bop1, and WDR12 controls nucleolar localization and assembly of the PeBoW complex required for maturation of the 60S ribosomal subunitHDM2-binding partners: interaction with translation elongation factor EF1alpha.The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNANVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequenceImpaired ribosome biogenesis in Diamond-Blackfan anemiaMitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1.Ribosomal protein S27L is a direct p53 target that regulates apoptosisMammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferationRegulation of nucleolar signalling to p53 through NEDDylation of L11MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikisInhibition of c-Myc activity by ribosomal protein L11MDMX regulation of p53 response to ribosomal stressRibosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulatorProteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradationRibosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domainThe role of human ribosomal proteins in the maturation of rRNA and ribosome productionRibosomal protein S9 is a novel B23/NPM-binding protein required for normal cell proliferationThe tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complexMutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stabilityDominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complexInhibition of HDM2 and activation of p53 by ribosomal protein L23Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionEssential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activationRibosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patientsAberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradationRegulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanismBystin in human cancer cells: intracellular localization and function in ribosome biogenesisMany ribosomal protein genes are cancer genes in zebrafishSynergistic defect in 60S ribosomal subunit assembly caused by a mutation of Rrs1p, a ribosomal protein L11-binding protein, and 3'-extension of 5S rRNA in Saccharomyces cerevisiaeThe importance of ribosome production, and the 5S RNP-MDM2 pathway, in health and diseaseTargeted cancer therapy with ribosome biogenesis inhibitors: a real possibility?Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instabilityDeubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1Perturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human disease
P2860
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P2860
Regulation of HDM2 activity by the ribosomal protein L11
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Regulation of HDM2 activity by the ribosomal protein L11
@ast
Regulation of HDM2 activity by the ribosomal protein L11
@en
Regulation of HDM2 activity by the ribosomal protein L11
@nl
type
label
Regulation of HDM2 activity by the ribosomal protein L11
@ast
Regulation of HDM2 activity by the ribosomal protein L11
@en
Regulation of HDM2 activity by the ribosomal protein L11
@nl
prefLabel
Regulation of HDM2 activity by the ribosomal protein L11
@ast
Regulation of HDM2 activity by the ribosomal protein L11
@en
Regulation of HDM2 activity by the ribosomal protein L11
@nl
P2093
P3181
P1433
P1476
Regulation of HDM2 activity by the ribosomal protein L11
@en
P2093
Karen H Vousden
Marion A E Lohrum
Mary Hanlon
Michael H G Kubbutat
Robert L Ludwig
P304
P3181
P356
10.1016/S1535-6108(03)00134-X
P407
P577
2003-06-01T00:00:00Z