Repair of and checkpoint response to topoisomerase I-mediated DNA damage
about
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage responseHistone H3 lysine 56 acetylation and the response to DNA replication fork damageA PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replicationRECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filamentsEffects of camptothecin on double-strand break repair by non-homologous end-joining in DNA mismatch repair-deficient human colorectal cancer cell linesPoly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase I-dependent recombination stimulation by P53Different Modes of Hydrogen Peroxide Action During Seed GerminationOxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegenerationThe role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapyCaenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediatesGenetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage.TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and IIA novel use of gentamicin in the ROS-mediated sensitization of NCI-H460 lung cancer cells to various anticancer agentsATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cellsTDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivoThe tumour suppressor CYLD regulates the p53 DNA damage responseExploring the cellular activity of camptothecin-triple-helix-forming oligonucleotide conjugates.BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.Deletion study of DNA topoisomerase IB from Leishmania donovani: searching for a minimal functional heterodimer.Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate Leishmania majorTOPOISOMERASE1α Acts through Two Distinct Mechanisms to Regulate Stele and Columella Stem Cell Maintenance.Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assayGEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombinationNitric oxide induces ataxia telangiectasia mutated (ATM) protein-dependent γH2AX protein formation in pancreatic β cells.HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair.The fission yeast Crb2/Chk1 pathway coordinates the DNA damage and spindle checkpoint in response to replication stress induced by topoisomerase I inhibitor.Synergistic targeting of cell membrane, cytoplasm, and nucleus of cancer cells using rod-shaped nanoparticlesRegulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription factorPhosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.DNA repair deficiency in neurodegeneration.SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline.Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway.A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response.Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells.APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination.Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage responseMutS homologue hMSH5: recombinational DSB repair and non-synonymous polymorphic variantsDeciphering cellular states of innate tumor drug responses.Coordination of DNA synthesis and replicative unwinding by the S-phase checkpoint pathways.
P2860
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P2860
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@ast
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@en
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@nl
type
label
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@ast
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@en
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@nl
prefLabel
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@ast
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@en
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@nl
P2093
P3181
P1433
P1476
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
@en
P2093
Christophe Redon
Glenda Kohlhagen
Haruyuki Takemura
HongLiang Zhang
Jennifer A Seiler
Kurt W Kohn
LingHua Meng
Olivier Sordet
Smitha Antony
V Ashutosh Rao
P304
P3181
P356
10.1016/J.MRFMMM.2003.08.016
P407
P50
P577
2003-11-27T00:00:00Z