Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid
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A human sleep homeostasis phenotype in mice expressing a primate-specific PER3 variable-number tandem-repeat coding-region polymorphismStimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out miceThree-dimensional structures of the three human class I alcohol dehydrogenasesLeukocyte homing, fate, and function are controlled by retinoic acidMetabolic methanol: molecular pathways and physiological rolesFormamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolismReduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometryBiosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenasesHominids adapted to metabolize ethanol long before human-directed fermentationExcessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidationRDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ developmentGenetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acidOpposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradationMerging protein, gene and genomic data: the evolution of the MDR-ADH family.Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes.Novel thioredoxin targets in Dictyostelium discoideum identified by two-hybrid analysis: interactions of thioredoxin with elongation factor 1alpha and yeast alcohol dehydrogenase.Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry.Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant miceA new view of alcohol metabolism and alcoholism--role of the high-Km Class III alcohol dehydrogenase (ADH3).Functions of Intracellular Retinoid Binding-Proteins.Contribution of NADH increases to ethanol's inhibition of retinol oxidation by human ADH isoforms.A novel suppressive effect of alcohol dehydrogenase 5 in neuronal differentiation.Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid.Quantification of endogenous retinoids.RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis.Studies of vitamin A metabolism in mouse model systems.Pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice after subchronic exposure to ethanolMetabolic conversion as a pre-receptor control mechanism for lipophilic hormones.Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo.Inhibiting vitamin A metabolism as an approach to male contraception.Primary follicular dystrophy with scarring dermatitis in C57BL/6 mouse substrains resembles central centrifugal cicatricial alopecia in humans.Transgenic mouse models for alcohol metabolism, toxicity, and cancer.Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout modelsRDH10 is the primary enzyme responsible for the first step of embryonic Vitamin A metabolism and retinoic acid synthesis.Endogenous retinoids in the hair follicle and sebaceous glandOntogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normalDissecting Germ Cell Metabolism through Network ModelingRole of retinoid signaling in the regulation of spermatogenesis.
P2860
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P2860
Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@ast
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@en
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@nl
type
label
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@ast
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@en
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@nl
prefLabel
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@ast
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@en
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@nl
P921
P356
P1476
Metabolic deficiencies in alco ...... sm of retinol to retinoic acid
@en
P2093
P304
P356
10.1074/JBC.274.24.16796
P407
P577
1999-06-11T00:00:00Z