Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidation
about
Kinetic mechanism of human class IV alcohol dehydrogenase functioning as retinol dehydrogenaseHuman aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolismStimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3Origins of the high catalytic activity of human alcohol dehydrogenase 4 studied with horse liver A317C alcohol dehydrogenaseHominids adapted to metabolize ethanol long before human-directed fermentationA vertebrate aldo-keto reductase active with retinoids and ethanol.Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant miceMetabolic conversion as a pre-receptor control mechanism for lipophilic hormones.Omega-oxidation of 20-hydroxyeicosatetraenoic acid (20-HETE) in cerebral microvascular smooth muscle and endothelium by alcohol dehydrogenase 4.Medium- and short-chain dehydrogenase/reductase gene and protein families : Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism.Expression of 17 genes in Clostridium thermocellum ATCC 27405 during fermentation of cellulose or cellobiose in continuous culture.Retinoic Acid Synthesis and Degradation.Distribution of alcohol dehydrogenase mRNA in the rat central nervous system. Consequences for brain ethanol and retinoid metabolism.Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract.Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase.The specificity of alcohol dehydrogenase with cis-retinoids. Activity with 11-cis-retinol and localization in retina.Synthesis of enantiopure C3- and C4-hydroxyretinals and their enzymatic reduction by ADH8 from Xenopus laevis.
P2860
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P2860
Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidation
description
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2000
@ast
im August 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/08/18)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/08/18)
@nl
наукова стаття, опублікована в серпні 2000
@uk
name
Molecular basis for differenti ...... m but not in ethanol oxidation
@ast
Molecular basis for differenti ...... m but not in ethanol oxidation
@en
Molecular basis for differenti ...... m but not in ethanol oxidation
@nl
type
label
Molecular basis for differenti ...... m but not in ethanol oxidation
@ast
Molecular basis for differenti ...... m but not in ethanol oxidation
@en
Molecular basis for differenti ...... m but not in ethanol oxidation
@nl
prefLabel
Molecular basis for differenti ...... m but not in ethanol oxidation
@ast
Molecular basis for differenti ...... m but not in ethanol oxidation
@en
Molecular basis for differenti ...... m but not in ethanol oxidation
@nl
P2093
P2860
P50
P356
P1476
Molecular basis for differenti ...... m but not in ethanol oxidation
@en
P2093
A Allali-Hassani
H Jörnvall
S E Martínez
P2860
P304
25180-25187
P356
10.1074/JBC.M910040199
P407
P577
2000-08-01T00:00:00Z