Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis.
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p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibitionZIP kinase triggers apoptosis from nuclear PML oncogenic domainsMEK5, a new target of the atypical protein kinase C isoforms in mitogenic signalingIdentification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cellsMechanisms of apoptosis by the tumor suppressor Par-4THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodiesDirect binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cellsDlk/ZIP kinase-induced apoptosis in human medulloblastoma cells: requirement of the mitochondrial apoptosis pathwayExpression and regulation of prostate apoptosis response-4 (Par-4) in human glioma stem cells in drug-induced apoptosisRegulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cellsNFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapyRegulation of mature T lymphocyte proliferation and differentiation by Par-4Protein kinase C isoforms: Multi-functional regulators of cell life and deathA novel adapter protein employs a phosphotyrosine binding domain and exceptionally basic N-terminal domains to capture and localize an atypical protein kinase C: characterization of Caenorhabditis elegans C kinase adapter 1, a protein that avidly biNuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda.Structural properties and mechanisms that govern association of C kinase adapter 1 with protein kinase C3 and the cell periphery.Function for NF-kB in neuronal survival: regulation by atypical protein kinase C.Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.Prostate apoptosis response-4 is expressed in normal cholangiocytes, is down-regulated in human cholangiocarcinoma, and promotes apoptosis of neoplastic cholangiocytes when induced pharmacologicallyThe atypical protein kinase Cs. Functional specificity mediated by specific protein adaptersApoptosis in amyotrophic lateral sclerosis: a review of the evidence.MAPK pathways in radiation responses.Prostate apoptosis response 4 (Par-4), a novel substrate of caspase-3 during apoptosis activation.It's a lipid's world: bioactive lipid metabolism and signaling in neural stem cell differentiation.Mechanisms of apoptosis during reovirus infection.PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways.Par-4 binds to topoisomerase 1 and attenuates its DNA relaxation activityApoptosis and tumor resistance conferred by Par-4Nephrin deficiency activates NF-kappaB and promotes glomerular injury.The Par-4/PTEN connection in tumor suppression.Cancer-selective apoptotic effects of extracellular and intracellular Par-4.pH-induced folding of an apoptotic coiled coil.Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling.Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells.Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survivalProteomics Analysis Reveals Novel RASSF2 Interaction Partners.Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis.Gene therapy that inhibits NF-kappaB results in apoptosis of human hepatocarcinoma by recombinant adenovirus.Genetic inactivation of Par4 results in hyperactivation of NF-kappaB and impairment of JNK and p38.Pro-apoptotic action of PAR-4 involves inhibition of NF-kappaB activity and suppression of BCL-2 expression.
P2860
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P2860
Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Inactivation of the inhibitory ...... actor alpha-induced apoptosis.
@en
Inactivation of the inhibitory ...... actor alpha-induced apoptosis.
@nl
type
label
Inactivation of the inhibitory ...... actor alpha-induced apoptosis.
@en
Inactivation of the inhibitory ...... actor alpha-induced apoptosis.
@nl
prefLabel
Inactivation of the inhibitory ...... actor alpha-induced apoptosis.
@en
Inactivation of the inhibitory ...... actor alpha-induced apoptosis.
@nl
P2093
P356
P1476
Inactivation of the inhibitory ...... actor alpha-induced apoptosis.
@en
P2093
P304
19606-19612
P356
10.1074/JBC.274.28.19606
P407
P577
1999-07-01T00:00:00Z