Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)
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Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2Negative regulation of cytokine signaling and immune responses by SOCS proteinsRegulation of Long Bone Growth in Vertebrates; It Is Time to Catch UpThe SOCS2 ubiquitin ligase complex regulates growth hormone receptor levelsSOCS2 negatively regulates growth hormone action in vitro and in vivoAging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophyInsulin regulates SOCS2 expression and the mitogenic effect of IGF-1 in mesangial cellsSuppressor of cytokine signaling 2 regulates neuronal differentiation by inhibiting growth hormone signalingSuppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.Favorable prognostic value of SOCS2 and IGF-I in breast cancer.Overexpression of Scg5 increases enzymatic activity of PCSK2 and is inversely correlated with body weight in congenic miceHigher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer.Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling.Knock your SOCS off!Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer.The FGFR4-G388R polymorphism promotes mitochondrial STAT3 serine phosphorylation to facilitate pituitary growth hormone cell tumorigenesisDirect stimulation of bone mass by increased GH signalling in the osteoblasts of Socs2-/- miceCrystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling.Regulation of TLR signaling and inflammation by SOCS family proteins.Nutrigenomics of hepatic steatosis in a feline model: effect of monosodium glutamate, fructose, and Trans-fat feedingA Point Mutation in Suppressor of Cytokine Signalling 2 (Socs2) Increases the Susceptibility to Inflammation of the Mammary Gland while Associated with Higher Body Weight and Size and Higher Milk Production in a Sheep Model.SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function.SOCS2 Balances Metabolic and Restorative Requirements during Liver Regeneration.Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network.SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function.Expansion of beta-cell mass in response to pregnancyThe growth hormone-insulin-like growth factor-I axis in chronic kidney diseaseInhibition of growth hormone signaling by the fasting-induced hormone FGF21.SOCS regulation of the JAK/STAT signalling pathway.Biology and significance of the JAK/STAT signalling pathways.Suppression of cytokine signaling: the SOCS perspective.The transcriptional response of the islet to pregnancy in mice.Age-associated alterations in the time-dependent profile of pro- and anti-inflammatory proteins within the hippocampus in response to acute exposure to interleukin-1β.SOCS proteins in development and disease.Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player.The C-terminus of CIS defines its interaction pattern.Cell regulation by phosphotyrosine-targeted ubiquitin ligases.Kinase inhibition, competitive binding and proteasomal degradation: resolving the molecular function of the suppressor of cytokine signaling (SOCS) proteins.Fibroblast growth factor 21: a regulator of metabolic disease and health span.
P2860
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P2860
Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)
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2002 nî lūn-bûn
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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@ast
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@en
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@nl
type
label
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@ast
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@en
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@nl
prefLabel
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@ast
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@en
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@nl
P2093
P50
P356
P1476
Growth enhancement in suppress ...... r of transcription 5b (STAT5b)
@en
P2093
Christopher J Greenhalgh
Helen W Davey
Jason E Corbin
Warren S Alexander
P304
P356
10.1210/MEND.16.6.0845
P407
P577
2002-06-01T00:00:00Z