Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain
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Direct demonstration of involvement of protein kinase Calpha in the Ca2+-induced platelet aggregationPhospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signalingCharacterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptorRac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerinDownregulation of Rap1GAP contributes to Ras transformationSTAC3 stably interacts through its C1 domain with CaV1.1 in skeletal muscle triadsCoordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.p23/Tmp21 associates with protein kinase Cdelta (PKCdelta) and modulates its apoptotic function.p23/Tmp21 differentially targets the Rac-GAP beta2-chimaerin and protein kinase C via their C1 domainsThe membrane and lipids as integral participants in signal transduction: lipid signal transduction for the non-lipid biochemist.Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes.Rac GTPase-activating protein (Rac GAP) α1-Chimaerin undergoes proteasomal degradation and is stabilized by diacylglycerol signaling in neurons.Nuclear transportation of diacylglycerol kinase gamma and its possible function in the nucleus.Protein kinase Cepsilon binds peripherin and induces its aggregation, which is accompanied by apoptosis of neuroblastoma cells.Rac signaling in breast cancer: a tale of GEFs and GAPs.Wealth of opportunity - the C1 domain as a target for drug development.Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling.Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.Antipsychotic drug treatment alters expression of mRNAs encoding lipid metabolism-related proteins.Identification of conserved amino acids N-terminal of the PKC epsilon C1b domain crucial for protein kinase C epsilon-mediated induction of neurite outgrowth.Identification of an amino acid residue in the protein kinase C C1b domain crucial for its localization to the Golgi network.Exchange factors of the RasGRP family mediate Ras activation in the Golgi.Identification of an autoinhibitory mechanism that restricts C1 domain-mediated activation of the Rac-GAP alpha2-chimaerinMembrane translocation of protein kinase Ctheta during T lymphocyte activation requires phospholipase C-gamma-generated diacylglycerol.The regulatory domain of protein kinase Ctheta localises to the Golgi complex and induces apoptosis in neuroblastoma and Jurkat cells.ARFGAP; cargo; v-SNAREs and p24 proteins bind nascent COPI complexARFGAP; cargo; vSNARES and p24 proteins bind COPI vesicles at Golgi
P2860
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P2860
Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@ast
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@en
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@nl
type
label
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@ast
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@en
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@nl
prefLabel
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@ast
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@en
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@nl
P2860
P356
P1476
Chimaerins, novel non-protein ...... olving the chimaerin C1 domain
@en
P2093
HongBin Wang
Marcelo G Kazanietz
P2860
P304
P356
10.1074/JBC.M107150200
P407
P577
2002-02-08T00:00:00Z