Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2 - Wikidata - awgldk - TriplyDB

Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2

Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2

http://www.wikidata.org/entity/Q28205086

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Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2 EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation Cysteine-based regulation of the CUL3 adaptor protein Keap1 Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damage Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia Crystal structure of quinone reductase 2 in complex with resveratrol Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein Reactive oxygen production induced by the gut microbiota: pharmacotherapeutic implications Arsenic responsive microRNAs in vivo and their potential involvement in arsenic-induced oxidative stress Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression Nrf2:INrf2 (Keap1) signaling in oxidative stress Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells.Transcriptome profiling of peripheral blood cells identifies potential biomarkers for doxorubicin cardiotoxicity in a rat model Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response The Keap1-Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases.CR6-interacting factor 1 (CRIF1) regulates NF-E2-related factor 2 (NRF2) protein stability by proteasome-mediated degradation.An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance The ubiquitin-conjugating enzyme UbcM2 can regulate the stability and activity of the antioxidant transcription factor Nrf2.Identification of a KEAP1 germline mutation in a family with multinodular goitre Mechanisms of Nrf2 protection in astrocytes as identified by quantitative proteomics and siRNA screening Ubiquitin-proteasome pathway and cellular responses to oxidative stress.Resveratrol attenuates inflammation and oxidative stress induced by myocardial ischemia-reperfusion injury: role of Nrf2/ARE pathway Atorvastatin attenuates inflammation and oxidative stress induced by ischemia/reperfusion in rat heart via the Nrf2 transcription factor Analysis of dimerization of BTB-IVR domains of Keap1 and its interaction with Cul3, by molecular modeling Glycosylation enables aesculin to activate Nrf2 The expression of heme oxygenase-1 induced by lansoprazole.Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2.Prevention of Streptozotocin-Induced Diabetic Nephropathy by MG132: Possible Roles of Nrf2 and IκB.The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice.Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway.Transcriptional regulation of the stress response by mTOR.Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors.Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.Bacillus amyloliquefaciens SC06 alleviates the oxidative stress of IPEC-1 via modulating Nrf2/Keap1 signaling pathway and decreasing ROS production.Novel insights into redox system and the mechanism of redox regulation.The role of modulation of antioxidant enzyme systems in the treatment of neurodegenerative diseases.

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Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2

http://www.wikidata.org/entity/Q28205086

description

2002 nî lūn-bûn

@nan

2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@ast

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@en

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@nl

type

label

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@ast

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@en

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@nl

prefLabel

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@ast

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@en

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

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P1476

Nrf2 degradation by the ubiqui ...... 32, the human homolog to INrf2

@en

P2093

Konjet R Sekhar

http://www.w3.org/2001/XMLSchema#string

Xue Xian Yan

http://www.w3.org/2001/XMLSchema#string

P2860

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Physical association of ubiquitin ligases and the 26S proteasome.

Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

P2888

P304

6829-6834

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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4537714

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P356

10.1038/SJ.ONC.1205905

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P407

P433

44

http://www.w3.org/2001/XMLSchema#string

P478

21

http://www.w3.org/2001/XMLSchema#string

P50

Michael L Freeman

P577

2002-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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11098048

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P6179

1031396867

http://www.w3.org/2001/XMLSchema#string

P698

12360409

http://www.w3.org/2001/XMLSchema#string

P921

ubiquitin-proteasome system