Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
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Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signalingDJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathwayKeap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damageRoles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degenerationNrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant inductionCrystal structure of quinone reductase 2 in complex with resveratrolAromatase Inhibitor-Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast CancerNuclear Factor-Erythroid-2-Related Factor 2 in Aging and Lung FibrosisPGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondriaStress-activated cap'n'collar transcription factors in aging and human diseaseRegulation of Nrf2-an updateThe complexity of the Nrf2 pathway: beyond the antioxidant responseAdaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemAntioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistanceNrf2 signaling and cell survivalNRF2-regulation in brain health and disease: implication of cerebral inflammationNrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio)Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 geneSalvianolic acid B attenuates toxin-induced neuronal damage via Nrf2-dependent glial cells-mediated protective activity in Parkinson's disease modelsNrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genesKeap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expressionNrf2:INrf2 (Keap1) signaling in oxidative stressDistinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stressProspective type 1 and type 2 disulfides of Keap1 protein.Time-dependent changes in ARE-driven gene expression by use of a noise-filtering process for microarray data.MCRS2 represses the transactivation activities of Nrf1.Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.Polymorphism of Nrf2, an antioxidative gene, is associated with blood pressure and cardiovascular mortality in hemodialysis patientsKeap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism.DNA sequence determinants of nuclear protein binding to the c-Ha-ras antioxidant/electrophile response element in vascular smooth muscle cells: identification of Nrf2 and heat shock protein 90 beta as heterocomplex components.An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundanceNrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.Chemistry of the cysteine sensors in Kelch-like ECH-associated protein 1Redox-based therapeutics in neurodegenerative disease.Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression.Ubiquitin-proteasome pathway and cellular responses to oxidative stress.
P2860
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P2860
Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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P356
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Functional characterization an ...... H:quinone oxidoreductase1 gene
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P2093
A K Jaiswal
S Dhakshinamoorthy
P2888
P304
P356
10.1038/SJ.ONC.1204506
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P577
2001-06-28T00:00:00Z
P5875
P6179
1012965063