Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.

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Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.

P2860

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Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.

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http://www.wikidata.org/entity/Q38582808

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2016 nî lūn-bûn

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2016年の論文

@ja

2016年論文

@yue

2016年論文

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2016年論文

@zh-hk

2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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Acetaminophen induces accumula ...... olyubiquitination dysfunction.

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Acetaminophen induces accumula ...... olyubiquitination dysfunction.

@en

prefLabel

Acetaminophen induces accumula ...... olyubiquitination dysfunction.

@en

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Acetaminophen induces accumula ...... olyubiquitination dysfunction.

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Masashi Takagi

http://www.w3.org/2001/XMLSchema#string

Masataka Santoh

http://www.w3.org/2001/XMLSchema#string

Seigo Sanoh

http://www.w3.org/2001/XMLSchema#string

Shigeru Ohta

http://www.w3.org/2001/XMLSchema#string

Yaichiro Kotake

http://www.w3.org/2001/XMLSchema#string

Yoko Ejiri

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases

Acetaminophen-induced hepatotoxicity

Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination

Structure and expression of the rat CYP3A1 gene: isolation of the gene (P450/6betaB) and characterization of the recombinant protein

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srep21373

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21373

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scholarly article

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10.1038/SREP21373

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English

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2016-02-22T00:00:00Z

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295686945

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1038017855

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26900149

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4761967

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Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.

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P2860

P2860

Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.

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P1476

P2093

P2860

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P356

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P6179

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P1476

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P2860

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P407

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P5875

P6179

P698

P932