The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndromePYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa BThe PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulationComparative analysis of apoptosis and inflammation genes of mice and humansDe novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseasesThe PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathwaysCARD games in apoptosis and immunityA comprehensive manually curated protein-protein interaction database for the Death Domain superfamilyHorror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragmentThe PYRIN domain: a member of the death domain-fold superfamilyPyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathwayNLRC5: a newly discovered MHC class I transactivator (CITA)Single-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes.Three-dimensional Structure of the NLRP7 Pyrin Domain: INSIGHT INTO PYRIN-PYRIN-MEDIATED EFFECTOR DOMAIN SIGNALING IN INNATE IMMUNITYStructure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome AssemblyNALPs: a novel protein family involved in inflammationInteraction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosisActivation and assembly of the inflammasomes through conserved protein domain familiesCARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.The PYRIN domain in signal transductionInhibiting the inflammasome: one domain at a timeUncoupling of Pyrin-only protein 2 (POP2)-mediated dual regulation of NF-κB and the inflammasomeAnalyses of six homologous proteins of Protochlamydia amoebophila UWE25 encoded by large GC-rich genes (lgr): a model of evolution and concatenation of leucine-rich repeatsThe death domain superfamily in intracellular signaling of apoptosis and inflammation.Increased frequency of Mediterranean fever gene variants in multiple myeloma.Nlrp2, a maternal effect gene required for early embryonic development in the mouseFunctional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.Nod2: a key regulator linking microbiota to intestinal mucosal immunity.The domains of apoptosis: a genomics perspective.PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.The NOD: a signaling module that regulates apoptosis and host defense against pathogens.Increased levels of circulating Annexin A5 in Familial Mediterranean fever.Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes.Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta productionAn updated view on the structure and function of PYRIN domains.Familial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic feverHigh Frequency of Inherited Variants in the MEFV Gene in Acute Lymphocytic Leukemia.
P2860
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P2860
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
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2000 nî lūn-bûn
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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@ast
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@en
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@nl
type
label
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@ast
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@en
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@nl
prefLabel
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@ast
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@en
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@nl
P356
P1476
The PYRIN domain: a novel motif found in apoptosis and inflammation proteins
@en
P2093
P S DiStefano
P2888
P304
P356
10.1038/SJ.CDD.4400774
P407
P577
2000-12-01T00:00:00Z