Copper-dependent autocleavage of glypican-1 heparan sulfate by nitric oxide derived from intrinsic nitrosothiols
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Glypican-1 mediates both prion protein lipid raft association and disease isoform formationPrion, amyloid beta-derived Cu(II) ions, or free Zn(II) ions support S-nitroso-dependent autocleavage of glypican-1 heparan sulfateVitamin C: update on physiology and pharmacologyInterleukin-1 beta induces posttranslational carboxymethylation and alterations in subnuclear distribution of lamin B in insulin-secreting RINm5F cellsNitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes.The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.Hemocyanin of the molluscan Concholepas concholepas exhibits an unusual heterodecameric array of subunits.Amyloid precursor protein (APP)/APP-like protein 2 (APLP2) expression is required to initiate endosome-nucleus-autophagosome trafficking of glypican-1-derived heparan sulfateSuppression of amyloid beta A11 antibody immunoreactivity by vitamin C: possible role of heparan sulfate oligosaccharides derived from glypican-1 by ascorbate-induced, nitric oxide (NO)-catalyzed degradation.Intracellular proteoglycans.Organ-specific heparan sulfate structural phenotypes.Heparan sulfate degradation products can associate with oxidized proteins and proteasomes.Rapid nuclear transit and impaired degradation of amyloid β and glypican-1-derived heparan sulfate in Tg2576 mouse fibroblasts.Copper-dependent co-internalization of the prion protein and glypican-1.Involvement of glycosylphosphatidylinositol-linked ceruloplasmin in the copper/zinc-nitric oxide-dependent degradation of glypican-1 heparan sulfate in rat C6 glioma cells.Distinct substrate specificities of bacterial heparinases against N-unsubstituted glucosamine residues in heparan sulfate.Hypoxia induces NO-dependent release of heparan sulfate in fibroblasts from the Alzheimer mouse Tg2576 by activation of nitrite reduction.
P2860
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P2860
Copper-dependent autocleavage of glypican-1 heparan sulfate by nitric oxide derived from intrinsic nitrosothiols
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@ast
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@en
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@nl
type
label
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@ast
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@en
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@nl
prefLabel
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@ast
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@en
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@nl
P2093
P356
P1476
Copper-dependent autocleavage ...... d from intrinsic nitrosothiols
@en
P2093
Fang Cheng
Katrin Mani
Lars-Ake Fransson
P304
33353-33360
P356
10.1074/JBC.M203383200
P407
P577
2002-06-25T00:00:00Z