The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.
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The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain InjuryAmyloid precursor protein and amyloid precursor-like protein 2 in cancerStructure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolutionAmyloid precursor protein (APP)/APP-like protein 2 (APLP2) expression is required to initiate endosome-nucleus-autophagosome trafficking of glypican-1-derived heparan sulfateCopper binding to the Alzheimer's disease amyloid precursor proteinProtease nexin-2/amyloid beta-protein precursor limits cerebral thrombosis.Analysis of the overall structure of the multi-domain amyloid precursor protein (APP).Suppression of amyloid beta A11 antibody immunoreactivity by vitamin C: possible role of heparan sulfate oligosaccharides derived from glypican-1 by ascorbate-induced, nitric oxide (NO)-catalyzed degradation.Transcriptomic Determinants of Scrapie Prion Propagation in Cultured Ovine Microglia.Functions of Aβ, sAPPα and sAPPβ : similarities and differences.Heparan sulfate degradation products can associate with oxidized proteins and proteasomes.Suppression of glypican-1 autodegradation by NO-deprivation correlates with nuclear accumulation of amyloid beta in normal fibroblasts.Rapid nuclear transit and impaired degradation of amyloid β and glypican-1-derived heparan sulfate in Tg2576 mouse fibroblasts.Role of Matricellular Proteins in Disorders of the Central Nervous System.LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent.Evaluation of Cu(i) binding to the E2 domain of the amyloid precursor protein - a lesson in quantification of metal binding to proteins via ligand competition.Reduced gliotransmitter release from astrocytes mediates tau-induced synaptic dysfunction in cultured hippocampal neurons.Hypoxia induces NO-dependent release of heparan sulfate in fibroblasts from the Alzheimer mouse Tg2576 by activation of nitrite reduction.Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis.Development of a reliable assay to measure glypican-1 in plasma and serum reveals circulating glypican-1 as a novel prostate cancer biomarker.Advanced fabrication of biosensor on detection of Glypican-1 using S-Acetylmercaptosuccinic anhydride (SAMSA) modification of antibody
P2860
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P2860
The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The amyloid precursor protein ...... can-1 heparan sulfate in vivo.
@ast
The amyloid precursor protein ...... can-1 heparan sulfate in vivo.
@en
type
label
The amyloid precursor protein ...... can-1 heparan sulfate in vivo.
@ast
The amyloid precursor protein ...... can-1 heparan sulfate in vivo.
@en
prefLabel
The amyloid precursor protein ...... can-1 heparan sulfate in vivo.
@ast
The amyloid precursor protein ...... can-1 heparan sulfate in vivo.
@en
P2093
P2860
P356
P1476
The amyloid precursor protein ...... can-1 heparan sulfate in vivo.
@en
P2093
B Elise Needham
Fang Cheng
Giuseppe D Ciccotosto
Katrin Mani
Lars-Ake Fransson
Roberto Cappai
P2860
P304
13913-13920
P356
10.1074/JBC.M409179200
P407
P577
2005-01-27T00:00:00Z