Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region
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Serotonin and dopamine protect from hypothermia/rewarming damage through the CBS/H2S pathwayHuman cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAMCharacterization of two pathogenic mutations in cystathionine beta-synthase: different intracellular locations for wild-type and mutant proteinsAutosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid bindingCBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutationsA pathogenic linked mutation in the catalytic core of human cystathionine beta-synthase disrupts allosteric regulation and allows kinetic characterization of a full-length dimerIMP dehydrogenase: structure, mechanism, and inhibition.IMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNAIntrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory siteDynamics of carbon monoxide binding to cystathionine beta-synthaseOne-Carbon Metabolism in Prostate Cancer: The Role of Androgen SignalingModeling cellular compartmentation in one-carbon metabolismDifferent characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoformsStructural basis of regulation and oligomerization of human cystathionine -synthase, the central enzyme of transsulfurationCBS domains: structure, function, and pathology in human proteinsDomain organization, catalysis and regulation of eukaryotic cystathionine beta-synthasesConformational properties of nine purified cystathionine β-synthase mutants.Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation.A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membraneGenetic analysis of the Staphylococcus epidermidis macromolecular synthesis operon: Serp1129 is an ATP binding protein and sigA transcription is regulated by both sigma(A)- and sigma(B)-dependent promoters.An unusual mutation results in the replacement of diaminopimelate with lanthionine in the peptidoglycan of a mutant strain of Mycobacterium smegmatis.Rescue of cystathionine beta-synthase (CBS) mutants with chemical chaperones: purification and characterization of eight CBS mutant enzymes.Molecular characterization of a cystathionine beta-synthase gene, CBS1, in Magnaporthe grisea.Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfurThe importance of the one carbon cycle nutritional support in human male fertility: a preliminary clinical reportMethionine-deficient diet induces post-transcriptional downregulation of cystathionine β-synthase.Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionineHigh homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations.Purification and characterization of cystathionine β-synthase bearing a cobalt protoporphyrin.Inter-domain communication of human cystathionine β-synthase: structural basis of S-adenosyl-L-methionine activation.Working with nitric oxide and hydrogen sulfide in biological systemsPLP-dependent H(2)S biogenesis.Mathematical analysis of the regulation of competing methyltransferasesFolding and activity of mutant cystathionine β-synthase depends on the position and nature of the purification tag: characterization of the R266K CBS mutantCystathionine beta-synthase mutants exhibit changes in protein unfolding: conformational analysis of misfolded variants in crude cell extracts.Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine β-synthase: a target for neuronal antioxidant defense.Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration.S-Adenosyl-l-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase.Purification, crystallization and preliminary crystallographic analysis of human cystathionine β-synthase.Purification, crystallization and preliminary crystallographic analysis of the full-length cystathionine β-synthase from Apis mellifera
P2860
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P2860
Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region
description
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im September 2001 veröffentlicher wissenschaftlicher Artikel
@de
scientific article (publication date: 4 September 2001)
@en
vedecký článok (publikovaný 2001/09/04)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/09/04)
@nl
наукова стаття, опублікована у вересні 2001
@uk
مقالة علمية (نشرت في 4-9-2001)
@ar
name
Regulation of human cystathion ...... omain in the C-terminal region
@ast
Regulation of human cystathion ...... omain in the C-terminal region
@en
Regulation of human cystathion ...... omain in the C-terminal region
@nl
type
label
Regulation of human cystathion ...... omain in the C-terminal region
@ast
Regulation of human cystathion ...... omain in the C-terminal region
@en
Regulation of human cystathion ...... omain in the C-terminal region
@nl
prefLabel
Regulation of human cystathion ...... omain in the C-terminal region
@ast
Regulation of human cystathion ...... omain in the C-terminal region
@en
Regulation of human cystathion ...... omain in the C-terminal region
@nl
P2093
P3181
P356
P1433
P1476
Regulation of human cystathion ...... omain in the C-terminal region
@en
P2093
P304
P3181
P356
10.1021/BI010711P
P407
P577
2001-09-04T00:00:00Z