Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis
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NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membraneDictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylationProtein kinases and phosphatases in the control of cell fateThe Novel Functions of the PLC/PKC/PKD Signaling Axis in G Protein-Coupled Receptor-Mediated Chemotaxis of NeutrophilsMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesBiophysical methods for the characterization of PTEN/lipid bilayer interactionsPtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanismPhosphoinositides: tiny lipids with giant impact on cell regulationThe role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migrationPTEN hopping on the cell membrane is regulated via a positively-charged C2 domainNovel protein Callipygian defines the back of migrating cells.Asymmetric PTEN distribution regulated by spatial heterogeneity in membrane-binding state transitionsKey role of local regulation in chemosensing revealed by a new molecular interaction-based modeling method.Ordered patterns of cell shape and orientational correlation during spontaneous cell migrationA glutamate switch controls voltage-sensitive phosphatase functionVoltage sensitive phosphatases: emerging kinship to protein tyrosine phosphatases from structure-function researchA phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activityNuclear localization of PTEN by a Ran-dependent mechanism enhances apoptosis: Involvement of an N-terminal nuclear localization domain and multiple nuclear exclusion motifsThe novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cellsStructural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerMembrane association of the PTEN tumor suppressor: electrostatic interaction with phosphatidylserine-containing bilayers and regulatory role of the C-terminal tail.Diffusion-limited phase separation in eukaryotic chemotaxis.Plasma membrane organization is essential for balancing competing pseudopod- and uropod-promoting signals during neutrophil polarization and migration.Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P3 response in dictyostelium cells.Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase.Imaging of cell migration.Spatial localization of m-calpain to the plasma membrane by phosphoinositide biphosphate binding during epidermal growth factor receptor-mediated activationChemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling.Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxisPhospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis.Self-organization of the phosphatidylinositol lipids signaling system for random cell migrationDelineating the core regulatory elements crucial for directed cell migration by examining folic-acid-mediated responsesPhase geometries of two-dimensional excitable waves govern self-organized morphodynamics of amoeboid cells.Group choreography: mechanisms orchestrating the collective movement of border cellsA mass conserved reaction-diffusion system captures properties of cell polarityQuantitative imaging of single live cells reveals spatiotemporal dynamics of multistep signaling events of chemoattractant gradient sensing in DictyosteliumElectrochemical coupling in the voltage-dependent phosphatase Ci-VSP.Moving in the right direction: how eukaryotic cells migrate along chemical gradients.Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.
P2860
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P2860
Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@ast
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@en
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@nl
type
label
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@ast
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@en
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@nl
prefLabel
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@ast
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@en
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@nl
P2093
P2860
P3181
P356
P1476
Novel mechanism of PTEN regula ...... tif is critical for chemotaxis
@en
P2093
Francisca Vazquez
Hongbo R Luo
Miho Iijima
Peter N Devreotes
Yi Elaine Huang
P2860
P304
P3181
P356
10.1074/JBC.M312098200
P407
P577
2004-04-16T00:00:00Z