The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis
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Fbxw7 Tumor Suppressor: A Vital Regulator Contributes to Human TumorigenesisThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaFBW7-mediated ubiquitination and degradation of KLF5Proteasome-mediated processing of Nrf1 is essential for coordinate induction of all proteasome subunits and p97Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymesGlycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1Transcription factor Nrf1 is negatively regulated by its O-GlcNAcylation statusFBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradationCharacterization of Nrf1b, a novel isoform of the nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genesAberrant regulation of FBW7 in cancer.Direct interaction between the WD40 repeat protein WDR-23 and SKN-1/Nrf inhibits binding to target DNA.Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domainsThe selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expressionTumor suppressor functions of FBW7 in cancer development and progression.Ubiquitin receptors and protein quality controlThe membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity.Recent advances in SCF ubiquitin ligase complex: Clinical implicationsExpression profiling and biochemical analysis suggest stress response as a potential mechanism inhibiting proliferation of polyamine-depleted cellsThe Transcriptional Network Structure of a Myeloid Cell: A Computational Approach.Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1
P2860
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P2860
The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis
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2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@ast
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@en
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@nl
type
label
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@ast
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@en
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@nl
prefLabel
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@ast
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@en
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@nl
P2093
P2860
P921
P356
P1476
The Fbw7 tumor suppressor regu ...... roteasome-mediated proteolysis
@en
P2093
Diane Phan
Jefferson Y Chan
Madhurima Biswas
Momoko Watanabe
P2860
P304
P356
10.1074/JBC.M111.253807
P407
P577
2011-11-11T00:00:00Z