DISC1 at 10: connecting psychiatric genetics and neuroscience
about
Toward developmental models of psychiatric disorders in zebrafishDISC1: a key lead in studying cortical development and associated brain disordersDISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disordersDISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial traffickingProphylactic valproic acid treatment prevents schizophrenia-related behaviour in Disc1-L100P mutant miceEarly postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1.Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models.Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging.Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion.New insights into behaviour using mouse ENU mutagenesisDIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling.Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes.An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.Category fluency, latent semantic analysis and schizophrenia: a candidate gene approachDisc1 variation leads to specific alterations in adult neurogenesis.DISC1 (disrupted-in-schizophrenia-1) regulates differentiation of oligodendrocytesDisordered ripples are a common feature of genetically distinct mouse models relevant to schizophrenia.Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.Modeling developmental neuropsychiatric disorders with iPSC technology: challenges and opportunitiesGenetic association of cyclic AMP signaling genes with bipolar disorder.Utility and validity of DISC1 mouse models in biological psychiatry.DISC1 as a Possible Genetic Contribution to Opioid Dependence in a Polish Sample.Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophreniaOpposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling.Association of schizophrenia with the rs821633 polymorphism in the DISC1 gene among Han ChineseCognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness.DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1.The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review.Common variants in psychiatric risk genes predict brain structure at birth.DISC1 as a therapeutic target for mental illnesses.DISC1 and SLC12A2 interaction affects human hippocampal function and connectivity.DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders.Are we getting closer to valid translational models for major depression?A review of the evidence for the canonical Wnt pathway in autism spectrum disorders.Progress in imaging the effects of psychosis susceptibility gene variants.Development and specification of GABAergic cortical interneuronsWnt and lithium: a common destiny in the therapy of nervous system pathologies?Glutamatergic postsynaptic density protein dysfunctions in synaptic plasticity and dendritic spines morphology: relevance to schizophrenia and other behavioral disorders pathophysiology, and implications for novel therapeutic approaches.Disturbance of oligodendrocyte function plays a key role in the pathogenesis of schizophrenia and major depressive disorder.
P2860
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P2860
DISC1 at 10: connecting psychiatric genetics and neuroscience
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2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
DISC1 at 10: connecting psychiatric genetics and neuroscience
@ast
DISC1 at 10: connecting psychiatric genetics and neuroscience
@en
DISC1 at 10: connecting psychiatric genetics and neuroscience
@nl
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DISC1 at 10: connecting psychiatric genetics and neuroscience
@ast
DISC1 at 10: connecting psychiatric genetics and neuroscience
@en
DISC1 at 10: connecting psychiatric genetics and neuroscience
@nl
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DISC1 at 10: connecting psychiatric genetics and neuroscience
@ast
DISC1 at 10: connecting psychiatric genetics and neuroscience
@en
DISC1 at 10: connecting psychiatric genetics and neuroscience
@nl
P2860
P1476
DISC1 at 10: connecting psychiatric genetics and neuroscience
@en
P2093
Akira Sawa
J Kirsty Millar
P2860
P304
P356
10.1016/J.MOLMED.2011.09.002
P407
P577
2011-12-01T00:00:00Z