Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
about
Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with MitofilinA nonsense mutation in the human homolog of Drosophila rogdi causes Kohlschutter-Tonz syndromeInteractome mapping suggests new mechanistic details underlying Alzheimer's diseaseDisc1 regulates granule cell migration in the developing hippocampusIdentifying gene regulatory networks in schizophreniaMutations in ROGDI Cause Kohlschütter-Tönz SyndromeDISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphismsMouse Genetic Models of Human Brain DisordersStress weakens prefrontal networks: molecular insults to higher cognitionSynapse-specific contributions in the cortical pathology of schizophreniaCellular reprogramming: recent advances in modeling neurological diseasesDISC1: a key lead in studying cortical development and associated brain disordersMissense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in miceDapper antagonist of catenin-1 cooperates with Dishevelled-1 during postsynaptic development in mouse forebrain GABAergic interneuronsCentriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplicationAutoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feelingDISC1 at 10: connecting psychiatric genetics and neuroscienceThe DISC locus in psychiatric illnessDISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial traffickingDISC1-binding proteins in neural development, signalling and schizophreniaTLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphologyDISC1: Structure, Function, and Therapeutic Potential for Major Mental IllnessDysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomesA simple cell-based assay reveals that diverse neuropsychiatric risk genes converge on primary ciliaProphylactic valproic acid treatment prevents schizophrenia-related behaviour in Disc1-L100P mutant miceThe inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cellsDisrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brainDISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formationMINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor functionDisrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1Wiki-pi: a web-server of annotated human protein-protein interactions to aid in discovery of protein functionSchizophrenia, "Just the Facts" 6. Moving ahead with the schizophrenia concept: from the elephant to the mouseDatabase of genetic studies of bipolar disorderNetwork medicine: a network-based approach to human diseaseGenetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.Potential primary roles of glial cells in the mechanisms of psychiatric disorders.Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models.Gene networks associated with conditional fear in mice identified using a systems genetics approach.Pre-clinical models of neurodevelopmental disorders: focus on the cerebellum
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Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
description
2007 nî lūn-bûn
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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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name
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@ast
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@en
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@en-gb
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@nl
type
label
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@ast
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@en
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@en-gb
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@nl
prefLabel
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@ast
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@en
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@en-gb
Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@nl
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P2860
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Disrupted in Schizophrenia 1 I ...... naptic basis for schizophrenia
@en
P2093
P2860
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P3181
P356
10.1038/SJ.MP.4001880
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2006-10-17T00:00:00Z
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P6179
1045536254