The ETO portion of acute myeloid leukemia t(8;21) fusion transcript encodes a highly evolutionarily conserved, putative transcription factor
about
The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressorsThe ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger proteinIdentification of homeotic target genes in Drosophila melanogaster including nervy, a proto-oncogene homologue.The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemiaETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domainDEAF-1, a novel protein that binds an essential region in a Deformed response elementIdentification of AML1-ETO modulators by chemical genomicsETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complexMolecular cloning and analysis of two subunits of the human TFIID complex: hTAFII130 and hTAFII100Association of MTG8 (ETO/CDR), a leukemia-related protein, with serine/threonine protein kinases and heat shock protein HSP90 in human hematopoietic cell linesMultiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins.Gfi/Pag-3/senseless zinc finger proteins: a unifying theme?The AML1/ETO fusion protein activates transcription of BCL-2RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis.The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability.Systems genetics implicates cytoskeletal genes in oocyte control of cloned embryo quality.Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.The leukemia associated nuclear corepressor ETO homologue genes MTG16 and MTGR1 are regulated differently in hematopoietic cellsThe t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation.Emerging Roles of MTG16 in Cell-Fate Control of Hematopoietic Stem Cells and Cancer.Characterization of RUNX1T1, an Adipogenesis Regulator in Ovine Preadipocyte Differentiation.
P2860
Q24324229-DFC17404-93EF-4E19-A6C3-6B5E83611305Q24522848-761342D2-05AB-4C8A-B690-0B5A8521FD89Q24523980-1065714A-19C0-4AA0-9533-DDCD81CC231BQ24533170-DF5E31E9-9B64-4956-8868-C7A952213AC4Q24545339-7D9CAA23-B5D7-4BC2-BBCE-ABA480B26F95Q24548340-60FD98D8-C49C-4B17-8807-8A3413D704F8Q24563096-D0BC038D-20C6-4CA8-ABB2-EEEB107DA0D2Q24643359-85437885-3E22-40E5-8269-467776D0B0A7Q24653699-3B905D33-4423-405E-9D0F-FA958104FD08Q24682969-F6FAE7A6-1A4D-4795-8323-67DEAD5EA152Q28138744-58923DC5-CE8E-4160-A000-DFDE138D2D6CQ34386755-9AA832D1-FEB8-4EBB-A905-24ED64F47163Q35905054-B926C514-14E8-423E-9676-D6B779608F89Q35942524-B870E7C1-6359-44BE-88DC-4BAAAF9DCEA5Q36206674-45053953-8FFB-4C56-86C9-914153A7D0F9Q36561099-2273A32F-C7BA-4834-9000-C17CE644994DQ36643897-227246C5-94F2-4459-B3A2-B6E1577965C2Q37273829-D06D74DB-62A1-4E68-8CD2-D90BDCB30334Q37679748-865F3CCB-8F19-4034-B0DA-CD3DC5EFDCA9Q39374868-BE049A0E-5B34-412E-87FD-C1542A16273EQ39631307-EC821450-FA56-4E0B-9BD7-265F480A900CQ48189669-95FD0438-F1D6-4D4E-82B1-630BF7755D9FQ52559173-1F52775A-3550-4851-BB6F-FCAE4D7DD3E5
P2860
The ETO portion of acute myeloid leukemia t(8;21) fusion transcript encodes a highly evolutionarily conserved, putative transcription factor
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
The ETO portion of acute myelo ...... putative transcription factor
@ast
The ETO portion of acute myelo ...... putative transcription factor
@en
The ETO portion of acute myelo ...... putative transcription factor
@nl
type
label
The ETO portion of acute myelo ...... putative transcription factor
@ast
The ETO portion of acute myelo ...... putative transcription factor
@en
The ETO portion of acute myelo ...... putative transcription factor
@nl
prefLabel
The ETO portion of acute myelo ...... putative transcription factor
@ast
The ETO portion of acute myelo ...... putative transcription factor
@en
The ETO portion of acute myelo ...... putative transcription factor
@nl
P2093
P1433
P1476
The ETO portion of acute myelo ...... putative transcription factor
@en
P2093
P304
P407
P577
1994-04-01T00:00:00Z