A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease - Wikidata - awgldk - TriplyDB

A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

http://www.wikidata.org/entity/Q28252463

about

Model systems of protein-misfolding diseases reveal chaperone modifiers of proteotoxicity Protein plasticity underlines activation and function of ATP-independent chaperones The struggle by Caenorhabditis elegans to maintain proteostasis during aging and disease HSP70 regulates the function of mitotic centrosomes The burden of trisomy 21 disrupts the proteostasis network in Down syndrome.The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases Dissecting the Molecular Mechanisms of Neurodegenerative Diseases through Network Biology Protein homeostasis of a metastable subproteome associated with Alzheimer's disease.The biology of proteostasis in aging and disease.Widespread Proteome Remodeling and Aggregation in Aging C. elegans.Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs Molecular Chaperones of Leishmania: Central Players in Many Stress-Related and -Unrelated Physiological Processes.Water-Transfer Slows Aging in Saccharomyces cerevisiae.The Chemical Biology of Molecular Chaperones--Implications for Modulation of Proteostasis A Differentiation Transcription Factor Establishes Muscle-Specific Proteostasis in Caenorhabditis elegans.Hyperactivity and attention deficits in mice with decreased levels of stress-inducible phosphoprotein 1 (STIP1).Hallmarks of therapeutic management of the cystic fibrosis functional landscape.The Social Amoeba Dictyostelium discoideum Is Highly Resistant to Polyglutamine Aggregation Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.A transcriptional signature of Alzheimer's disease is associated with a metastable subproteome at risk for aggregation Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.Protein aggregation activates erratic stress response in dietary restricted yeast cells.Quantitative proteomics of rat livers shows that unrestricted feeding is stressful for proteostasis with implications on life span.Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan.Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans.Royal jelly promotes DAF-16-mediated proteostasis to tolerate β-amyloid toxicity in C. elegans model of Alzheimer's disease.Protein misfolding in neurodegenerative diseases: implications and strategies.Molecular chaperones and neuronal proteostasis.Proteostasis and aging.Walking the tightrope: proteostasis and neurodegenerative disease.The epichaperome is an integrated chaperome network that facilitates tumour survival Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates.RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology.Embryonic stem cells: a novel paradigm to study proteostasis?Understanding and predicting protein misfolding and aggregation: Insights from proteomics.Prions, Chaperones, and Proteostasis in Yeast.When proteostasis goes bad: Protein aggregation in the cell.Cellular Regulation of Amyloid Formation in Aging and Disease.

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

http://www.wikidata.org/entity/Q28252463

description

2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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J.CELREP.2014.09.042

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A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease

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Adriana Villella

http://www.w3.org/2001/XMLSchema#string

Cindy Voisine

http://www.w3.org/2001/XMLSchema#string

Dan Garza

http://www.w3.org/2001/XMLSchema#string

Hui Ge

http://www.w3.org/2001/XMLSchema#string

James H Soper

http://www.w3.org/2001/XMLSchema#string

Kai Orton

http://www.w3.org/2001/XMLSchema#string

Marc Vidal

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Richard I Morimoto

http://www.w3.org/2001/XMLSchema#string

Shinichiro Wachi

http://www.w3.org/2001/XMLSchema#string

Yitan Zhu

http://www.w3.org/2001/XMLSchema#string

P2860

Database resources of the National Center for Biotechnology Information

A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons

The genetics of Caenorhabditis elegans

Formation of membrane-bound ring complexes by prohibitins in mitochondria

The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory

InterPro in 2011: new developments in the family and domain prediction database

WormBase: a comprehensive resource for nematode research

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons

A genetic screening strategy identifies novel regulators of the proteostasis network

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neurodegeneration

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