about
The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skinCoupling of the nucleus and cytoplasm: role of the LINC complexTargeting protein prenylation in progeriaBlocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndromeProgerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblastsAltered protein dynamics of disease-associated lamin A mutantsAnalysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartmentEmbryonic senescence and laminopathies in a progeroid zebrafish modelA pathway linking oxidative stress and the Ran GTPase system in progeria.Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport.Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human agingNuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targetingDiseases of the nuclear envelope.Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.The posttranslational processing of prelamin A and disease.LMNA Sequences of 60,706 Unrelated Individuals Reveal 132 Novel Missense Variants in A-Type Lamins and Suggest a Link between Variant p.G602S and Type 2 DiabetesMechanobiology and the microcirculation: cellular, nuclear and fluid mechanics.An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.Nuclear lamins and neurobiology.Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of lamin A/CThe lamin protein family.A mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorderRapamycin treatment of Mandibuloacral dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamicsInvestigating the purpose of prelamin A processingType B mandibuloacral dysplasia with congenital myopathy due to homozygous ZMPSTE24 missense mutation.Homozygous null mutations in ZMPSTE24 in restrictive dermopathy: evidence of genetic heterogeneitySulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts.New ZMPSTE24 (FACE1) mutations in patients affected with restrictive dermopathy or related progeroid syndromes and mutation update.A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells.Mislocalization of prelamin A Tyr646Phe mutant to the nuclear pore complex in human embryonic kidney 293 cells.Hallermann-Streiff Syndrome: No Evidence for a Link to Laminopathies.Mouse models of the laminopathies.Understanding the roles of nuclear A- and B-type lamins in brain development.Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24Analysis of nuclear lamin isoprenylation in Xenopus oocytes: isoprenylation of lamin B3 precedes its uptake into the nucleus.Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor.Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties.Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution.Regulation of nuclear lamin polymerization by importin alpha.
P2860
Q21144407-F53C4C8F-5018-45FD-A1D7-6FC37851BC1BQ24299991-9B3721DD-E5B2-4012-9582-C3B49B0C1500Q24594564-8F8F8C14-37C2-40EE-92A1-E66D27123671Q24627329-0E9C789B-B9C5-4FF4-8A48-1BD934B05E0FQ24634195-9F1E7ECA-2297-46DA-B7CE-E95D1BF59AD1Q24791233-D075D9F4-1AC8-48B3-90A2-C7473CB15312Q27939423-21DD8148-4BCC-4F05-881F-0F96AC056770Q28477557-B09876EC-54C0-4607-9E53-5F61A77868DCQ30412267-30F51C79-AE77-4642-83AC-4366691B942DQ30416354-1744870D-9EBF-46CA-8F36-4910041F71A3Q30479111-F9611C2D-CFDF-4033-B646-1F4EF60A53AEQ33638752-78C7B98F-131B-4B96-87C9-A674DAF31C11Q33687043-5A90E40C-06C2-4DD6-A26B-DA088CC79785Q33755858-C0B3D360-0B92-4C48-90C3-BF698A360853Q33758494-D3895BB0-FEFF-494C-8113-CEB6AFB3272FQ33799816-ECB68AAB-55B4-44E1-8865-1870FBBF2AE7Q33895715-094B4C06-0228-4978-8DB1-AC758FFE7D2BQ33904465-EB507A51-C9A0-4CE8-984B-0B30D2CF9D60Q33966782-B445CF31-E4C8-407C-A4A3-56DD8A78EC24Q34056472-E43880B7-D2D9-4F5C-958B-36CE78F1D506Q34145499-DA3B03E4-E37F-48E0-980B-E5A8636C768DQ34189692-514BDEAD-64C8-4A28-A4DB-F3FB4FA85487Q34520494-BC2E87FE-EFC8-417D-A93B-9D0C090062EAQ34520717-42F4AF0F-9C7F-4F1F-92C8-663C32DAD686Q35015891-9E1551AE-81D1-4829-AD11-C764DE4D67B9Q35030979-F58ABAA3-971D-414D-9C96-B8F1F41DBDC2Q35050744-69525E99-9BDF-4941-83C6-0D8CABFE5E6CQ35080536-78BDFEEF-C8F9-4581-89B7-0D6AF3513627Q35150458-343324DA-6E17-4F49-A694-F9A1D0160E0DQ35677842-458CDBE1-5A8A-4C4A-A7E7-C781D79FBFFAQ35748457-2EDB2679-E6BE-4C09-913F-F20E9AA1AD69Q35932635-F050A54B-203F-4941-ACF0-139862C7FBE6Q35942479-467BD9C1-4BFA-4CC2-A9BC-39E5413163B2Q35956784-72146481-DC71-4BC3-921F-BC788AFA1876Q35958478-6991B76E-2668-4529-BC67-D1B6613E219AQ36235322-469CD8E6-C160-498F-A781-086B5E8797AAQ36259400-D30E6B78-BE71-4F82-BCA5-7E872971774FQ36286147-36A54117-5BD2-4EEB-80D6-37EDFCC6A672Q36338746-98772A43-A2BC-4C8B-AA65-2E3AA3EA11AAQ36704134-7D0D1897-A45E-4806-A572-B2ED9E535E0D
P2860
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
The processing pathway of prelamin A
@ast
The processing pathway of prelamin A
@en
The processing pathway of prelamin A
@nl
type
label
The processing pathway of prelamin A
@ast
The processing pathway of prelamin A
@en
The processing pathway of prelamin A
@nl
prefLabel
The processing pathway of prelamin A
@ast
The processing pathway of prelamin A
@en
The processing pathway of prelamin A
@nl
P2093
P3181
P1476
The processing pathway of prelamin A
@en
P2093
P3181
P407
P478
107 ( Pt 1)
P577
1994-01-01T00:00:00Z