Conservation of sequence in recombination signal sequence spacers
about
RAG1 core and V(D)J recombination signal sequences were derived from Transib transposonsIdentification and utilization of arbitrary correlations in models of recombination signal sequencesA functional analysis of the spacer of V(D)J recombination signal sequencesMolecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsisEvolution of the recombination signal sequences in the Ig heavy-chain variable region locus of mammalsPatterns of receptor revision in the immunoglobulin heavy chains of a teleost fishConserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells.Illegitimate V(D)J recombination-mediated deletions in Notch1 and Bcl11b are not sufficient for extensive clonal expansion and show minimal age or sex bias in frequency or junctional processing.Synapsis alters RAG-mediated nicking at Tcrb recombination signal sequences: implications for the “beyond 12/23” ruleDetection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking.Postcleavage sequence specificity in V(D)J recombination.Multiple factors influence the contribution of individual immunoglobulin light chain genes to the naïve antibody repertoireEarly development of non-hodgkin lymphoma following initiation of newer class antiretroviral therapy among HIV-infected patients - implications for immune reconstitutionContribution of V(H) replacement products in mouse antibody repertoire.Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage.Accumulation of VH Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human.Evolution of the porcine (Sus scrofa domestica) immunoglobulin kappa locus through germline gene conversion.Organization, complexity and allelic diversity of the porcine (Sus scrofa domestica) immunoglobulin lambda locusAncestry influences the fate of duplicated genes millions of years after polyploidization of clawed frogs (Xenopus)Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage.Recruitment of RAG1 and RAG2 to Chromatinized DNA during V(D)J Recombination.The beyond 12/23 restriction is imposed at the nicking and pairing steps of DNA cleavage during V(D)J recombination.Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling.Sequence of the spacer in the recombination signal sequence affects V(D)J rearrangement frequency and correlates with nonrandom Vkappa usage in vivoDNA sequence and structure requirements for cleavage of V(D)J recombination signal sequencesCollaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination.Full-length RAG1 promotes contact with coding and intersignal sequences in RAG protein complexes bound to recombination signals paired in cis.An activation-induced cytidine deaminase-independent mechanism of secondary VH gene rearrangement in preimmune human B cellsA defective Vkappa A2 allele in Navajos which may play a role in increased susceptibility to haemophilus influenzae type b diseaseAn amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1.Synapsis of recombination signal sequences located in cis and DNA underwinding in V(D)J recombination.Effect of CpG methylation on RAG1/RAG2 reactivity: implications of direct and indirect mechanisms for controlling V(D)J cleavage.The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer.New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination.A Novel Quantitative Fluorescent Reporter Assay for RAG Targets and RAG Activity.The effect of Me2+ cofactors at the initial stages of V(D)J recombination.Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination.Secondary mechanisms of diversification in the human antibody repertoire.Deep sequencing of the murine IgH repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies.
P2860
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P2860
Conservation of sequence in recombination signal sequence spacers
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Conservation of sequence in recombination signal sequence spacers
@ast
Conservation of sequence in recombination signal sequence spacers
@en
Conservation of sequence in recombination signal sequence spacers
@nl
type
label
Conservation of sequence in recombination signal sequence spacers
@ast
Conservation of sequence in recombination signal sequence spacers
@en
Conservation of sequence in recombination signal sequence spacers
@nl
prefLabel
Conservation of sequence in recombination signal sequence spacers
@ast
Conservation of sequence in recombination signal sequence spacers
@en
Conservation of sequence in recombination signal sequence spacers
@nl
P2093
P2860
P356
P1476
Conservation of sequence in recombination signal sequence spacers
@en
P2093
P2860
P304
P356
10.1093/NAR/22.10.1785
P407
P577
1994-05-25T00:00:00Z