Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary
about
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activationDistinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreasAck1 tyrosine kinase activation correlates with pancreatic cancer progressionGermline PTEN mutations in Cowden syndrome-like families.The genetics of transitional cell carcinoma: progress and potential clinical application.Expression of the DMBT1 gene is frequently suppressed in human lung cancer.Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cellsPTEN loss accelerates KrasG12D-induced pancreatic cancer developmentPolymorphisms in PTEN in breast cancer families.ACK1/TNK2 tyrosine kinase: molecular signaling and evolving role in cancers.Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinomaGenetic deletion and pharmacological inhibition of Akt1 isoform attenuates bladder cancer cell proliferation, motility and invasion.Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas.Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1.Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas.TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells.Integrative survival-based molecular profiling of human pancreatic cancer.Loss of phosphatase and tensin homolog expression is associated with recurrence and poor prognosis in patients with pancreatic ductal adenocarcinoma.Metabolism addiction in pancreatic cancer.Mutational analysis of the PTEN/MMAC1 gene in primary oesophageal squamous cell carcinomas.The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells.PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells.TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells.Akt activation in renal cell carcinoma: contribution of a decreased PTEN expression and the induction of apoptosis by an Akt inhibitor.In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer.Essential role of Notch signaling in apoptosis of human pancreatic tumoral cells mediated by exosomal nanoparticles.Loss of tumor suppressor protein PTEN during renal carcinogenesis.Frequent nuclear accumulation of beta-catenin in pituitary adenoma.Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer.Infrequent mutation of APC, AXIN1, and GSK3B in human pituitary adenomas with abnormal accumulation of CTNNB1.The PTEN, BAX, and IGFIIR genes are mutated in endometrial atypical hyperplasia.
P2860
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P2860
Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@ast
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@en
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@nl
type
label
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@ast
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@en
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@nl
prefLabel
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@ast
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@en
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@nl
P2093
P2860
P1476
Infrequent genetic alterations ...... g, pancreas, kidney, and ovary
@en
P2093
A Sakurada
H Yamakawa
S Fujimura
P2860
P304
P356
10.1111/J.1349-7006.1997.TB00324.X
P407
P577
1997-11-01T00:00:00Z