Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.
about
The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer.Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsThe molecular fingerprint of high grade serous ovarian cancer reflects its fallopian tube originAkt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer.PTEN: one gene, many syndromesBeta1,4-galactosyltransferase V functions as a positive growth regulator in gliomaPhosphorylation state-specific antibodies: applications in investigative and diagnostic pathology.RFP-mediated ubiquitination of PTEN modulates its effect on AKT activationProteome profile changes that are differentially regulated by lipid and protein phosphatase activities of tumor suppressor PTEN in PTEN-expressing U-87 MG human glioblastoma cells.Histological evaluation of AMPK signalling in primary breast cancerGrowth suppression of human lung cancer cells and implanted tumors by adenovirus-mediated transfer of the PTEN gene.The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathwayEndometrial cancer: what is new in adjuvant and molecularly targeted therapy?A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance.Genetics of endometrial cancersFocal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer.Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo.Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression.PTEN as a prognostic and predictive marker in postoperative radiotherapy for squamous cell cancer of the head and neck.PTEN transcript variants caused by illegitimate splicing in "aged" blood samples and EBV-transformed cell lines.REDD1 and p-AKT over-expression may predict poor prognosis in ovarian cancerActivation of miR-21 by STAT3 induces proliferation and suppresses apoptosis in nasopharyngeal carcinoma by targeting PTEN geneDistinct gene expression profiles in ovarian cancer linked to Lynch syndromeThymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cellsMultiple genetic alterations within the PI3K pathway are responsible for AKT activation in patients with ovarian carcinomaA multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas.Dual targeting of phosphoinositide 3-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma.Cytogenetics and molecular genetics of ovarian cancer.Phase II trial of bevacizumab in recurrent or persistent endometrial cancer: a Gynecologic Oncology Group studyMechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cellsOncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells.Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway.Genomic complexity and AKT dependence in serous ovarian cancer.PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers.Considerations when analyzing the methylation status of PTEN tumor suppressor gene.Evidence for PTEN-independent Akt activation and Akt-independent p27(Kip1) expression in advanced bladder cancer.EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expressionThe association of PI3 kinase signaling and chemoresistance in advanced ovarian cancer.A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population.Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations.
P2860
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P2860
Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Frequent loss of PTEN expressi ...... epithelial ovarian carcinomas.
@ast
Frequent loss of PTEN expressi ...... epithelial ovarian carcinomas.
@en
type
label
Frequent loss of PTEN expressi ...... epithelial ovarian carcinomas.
@ast
Frequent loss of PTEN expressi ...... epithelial ovarian carcinomas.
@en
prefLabel
Frequent loss of PTEN expressi ...... epithelial ovarian carcinomas.
@ast
Frequent loss of PTEN expressi ...... epithelial ovarian carcinomas.
@en
P2093
P2860
P1476
Frequent loss of PTEN expressi ...... epithelial ovarian carcinomas.
@en
P2093
P2860
P304
P356
10.1016/S0002-9440(10)64681-0
P407
P577
2001-06-01T00:00:00Z