ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage
about
The replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplicationReplication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cellsReplication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast.Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakageGlobal regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.Network architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis.Chk1 promotes replication fork progression by controlling replication initiation.Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteinsRad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity.Replication licensing and the DNA damage checkpoint.The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism.Regulation of the cellular DNA double-strand break response.Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells.LIM Protein Ajuba Participates in the Repression of the ATR-Mediated DNA Damage ResponseSurvival of the replication checkpoint deficient cells requires MUS81-RAD52 function.RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.DNA replication origin interference increases the spacing between initiation events in human cells.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases.Onset of the DNA replication checkpoint in the early Drosophila embryo.Increased common fragile site expression, cell proliferation defects, and apoptosis following conditional inactivation of mouse Hus1 in primary cultured cells.Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1.Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.Chk1 Activation Protects Rad9A from Degradation as Part of a Positive Feedback Loop during Checkpoint Signalling.Checking on DNA damage in S phase.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forksKinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA.Cell-cycle regulation of cohesin stability along fission yeast chromosomesRepair of topoisomerase I-mediated DNA damage.Back to the origin: reconsidering replication, transcription, epigenetics, and cell cycle control.Recruitment and activation of Chk1Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts.SUMO2/3 modification of cyclin E contributes to the control of replication origin firing.Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpointCell cycle studies based upon quantitative image analysis.DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress.DNA replication and spindle checkpoints cooperate during S phase to delay mitosis and preserve genome integrityThe Intra-S Checkpoint Responses to DNA Damage.Over expression of hRad9 protein correlates with reduced chemosensitivity in breast cancer with administration of neoadjuvant chemotherapy.ATR: a master conductor of cellular responses to DNA replication stress.
P2860
Q24633729-3A8936B8-3663-4872-B38E-E364AD26489CQ24679451-A1444DBD-FD03-4D33-A4B2-F4B61E09E5F2Q30479065-F6734993-CE02-4E95-97FA-45437DD6583DQ31160033-8B80F7FA-0AFB-4207-BF6B-B704A0E3B978Q33314935-0A5C7B88-9C83-40B5-831E-91460B8A033FQ33474752-799F4D17-C4B9-4B3F-A5E1-3B3392AD5210Q34136566-9447A5D8-B669-4202-B345-3BD7730F3247Q34457674-F48B2F67-CCD5-4A86-9AFE-8CF7333B6DC7Q34478130-EDDE5EC5-DFD5-4EE4-9058-7CDE75F32C19Q34547673-1A2A5E3C-9152-49C5-ADE6-454F2D1B0EF7Q34557750-44AD8133-6557-46E8-A03E-64D7CF2A5FF1Q34722112-EB4A0767-89EC-41C6-833A-D7C23BD1C9C7Q34755147-88D25EBA-1790-4D1B-B446-862C23BE463FQ34765484-BEFCFC63-B2B8-4D4F-816D-2DC7D48A945EQ35034362-9CD01CB6-0668-4A12-8632-4F386DC40C1CQ35116809-9A85A8C9-EB54-4970-8E3A-CB5919466BBBQ35191023-2CA31A46-A95F-4ACE-9BA3-B9BD1B2E0A67Q35205026-9F0B06FD-A7E3-4CC0-A2BE-2F50F690EDFAQ35207086-C7EFACB0-0C35-4B09-BF97-AC2FE7C0F4E7Q35641483-14DEEC1B-77A0-4EF2-8507-CCCCC762A4FDQ35650781-FC15788E-B488-4092-B31C-4AC53F47CECEQ35676284-6466D753-111D-4E6C-BE92-B7B6E0A35514Q35676646-F04BAFE5-CEDB-40AB-91D8-829A2F570C23Q35867102-95729A4B-20CE-4F17-916A-F00AF887DAD3Q35906070-F60C5982-39D4-47C6-A08F-2D2F8CA46516Q35953858-5C7B7F69-A94C-4DA3-A4FC-02214E60A967Q35983115-6E71D986-25A2-463E-B2DD-98CA1439A9B7Q36392012-8AEB8A04-C34B-449C-9653-9E4BC8032EE0Q36557533-50363292-A162-4D7A-82BD-2534D6326D2BQ36796433-E3A5CCCB-87A2-41D0-A7A9-01DA62DB1482Q36811950-998EEA9E-FDBF-46CD-8498-7DEC10A1D73FQ36891684-1F8B70CD-400E-4810-A84B-F51A9EB80AEBQ36906799-07917097-F7DA-45E7-8C12-DD0E6D7D3E0BQ36923333-9D4C68B3-AC9C-46DA-9E0F-6FDE1369EC26Q37046684-8FC1613C-2969-422F-B57B-A957D69C8748Q37418404-90B5B6F1-C7F9-4EC4-8DE1-871D179E25F2Q37498597-36B37B48-3108-4E89-B221-306A19E635A7Q37676255-F0F162A3-0C2A-479E-9B73-A743BA0EF37DQ37736274-BE6AF1A0-CFAC-4F1B-9DC9-68295F929F65Q37800265-104DAE23-3958-41D7-982D-4014C198B5EE
P2860
ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@ast
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@en
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@nl
type
label
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@ast
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@en
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@nl
prefLabel
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@ast
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@en
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@nl
P356
P1433
P1476
ATR, Claspin and the Rad9-Rad1 ...... A in the absence of DNA damage
@en
P2093
Claus Storgaard Sørensen
Randi G Syljuåsen
P356
10.4161/CC.3.7.972
P407
P577
2004-07-01T00:00:00Z