Skin-derived antileukoproteinase (SKALP), an elastase inhibitor from human keratinocytes. Purification and biochemical properties
about
Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessingCharacterization and gene sequence of the precursor of elafin, an elastase-specific inhibitor in bronchial secretionsThe trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide coreConstitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epitheliaSKALP/elafin gene polymorphisms are not associated with pustular forms of psoriasisDirect evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelopeThe proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelopeCloning of a gene for a novel epithelium-specific cytosolic phospholipase A2, cPLA2delta, induced in psoriatic skin.Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:CA functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of the oesophagusAccelerated evolution in inhibitor domains of porcine elafin family members.Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.Antibacterial activity of antileukoprotease.Adenoviral E1A suppresses secretory leukoprotease inhibitor and elafin secretion in human alveolar epithelial cells and bronchial epithelial cells.Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung.Secretion of mucus proteinase inhibitor and elafin by Clara cell and type II pneumocyte cell lines.Structural organization of cornified cell envelopes and alterations in inherited skin disorders.Differential expression of SKALP/Elafin in human epidermal tumors.Increased elafin expression in cystic, dysplastic and neoplastic oral tissues.The antimicrobial antiproteinase elafin binds to lipopolysaccharide and modulates macrophage responses.Identification and sequence analysis of two new members of the SKALP/elafin and SPAI-2 gene family. Biochemical properties of the transglutaminase substrate motif and suggestions for a new nomenclature.Elafin is induced in epidermis in skin disorders with dermal neutrophilic infiltration: interleukin-1 beta and tumour necrosis factor-alpha stimulate its secretion in vitro.
P2860
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P2860
Skin-derived antileukoproteinase (SKALP), an elastase inhibitor from human keratinocytes. Purification and biochemical properties
description
1991 nî lūn-bûn
@nan
1991 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Skin-derived antileukoproteina ...... ion and biochemical properties
@ast
Skin-derived antileukoproteina ...... ion and biochemical properties
@en
Skin-derived antileukoproteina ...... ion and biochemical properties
@nl
type
label
Skin-derived antileukoproteina ...... ion and biochemical properties
@ast
Skin-derived antileukoproteina ...... ion and biochemical properties
@en
Skin-derived antileukoproteina ...... ion and biochemical properties
@nl
prefLabel
Skin-derived antileukoproteina ...... ion and biochemical properties
@ast
Skin-derived antileukoproteina ...... ion and biochemical properties
@en
Skin-derived antileukoproteina ...... ion and biochemical properties
@nl
P2093
P1476
Skin-derived antileukoproteina ...... ion and biochemical properties
@en
P2093
G J de Jongh
J Schalkwijk
P304
P356
10.1016/0925-4439(91)90053-C
P407
P577
1991-02-22T00:00:00Z