The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core
about
The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung diseaseWFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lungHuman epididymis protein-4 (HE-4): a novel cross-class protease inhibitorNew look at the role of progerin in skin agingAntimicrobial peptides in the female reproductive tract: a critical component of the mucosal immune barrier with physiological and clinical implicationsSecretory leukocyte protease inhibitor (SLPI) is, like its homologue trappin-2 (pre-elafin), a transglutaminase substrateEvolution of trappin genes in mammalsComparative sequence analyses reveal rapid and divergent evolutionary changes of the WFDC locus in the primate lineageIdentification of novel functional sequence variants in the gene for peptidase inhibitor 3.Plasma neutrophil elastase and elafin imbalance is associated with acute respiratory distress syndrome (ARDS) development.Structural and antimicrobial properties of human pre-elafin/trappin-2 and derived peptides against Pseudomonas aeruginosa.Anti-inflammatory and antimicrobial roles of secretory leukocyte protease inhibitor.Human immunodeficiency virus type 1 stimulates the expression and production of secretory leukocyte protease inhibitor (SLPI) in oral epithelial cells: a role for SLPI in innate mucosal immunityAntimicrobial activity of murine lung cells against Staphylococcus aureus is increased in vitro and in vivo after elafin gene transfer.Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome.The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:CAnti-HIV-1 activity of elafin depends on its nuclear localization and altered innate immune activation in female genital epithelial cells.HE4 as a biomarker for ovarian and endometrial cancer management.Pathophysiology of generalized pustular psoriasis.Regulation of pulmonary and systemic bacterial lipopolysaccharide responses in transgenic mice expressing human elafinA functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.Anti-HIV-1 activity of elafin is more potent than its precursor's, trappin-2, in genital epithelial cellsRespiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidantsRoles of transglutaminases in cardiac and vascular diseases.A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS.Human rElafin Inhibits HIV-1 Replication in Its Natural Target Cells.Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein sheddingAntiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.Innate host defense functions of secretory leucoprotease inhibitor.Intracellular secretory leukoprotease inhibitor modulates inositol 1,4,5-triphosphate generation and exerts an anti-inflammatory effect on neutrophils of individuals with cystic fibrosis and chronic obstructive pulmonary disease.Genetic polymorphisms of peptidase inhibitor 3 (elafin) are associated with acute respiratory distress syndrome.Proteomics analysis of conditioned media from three breast cancer cell lines: a mine for biomarkers and therapeutic targets.HE4-test of urine and body fluids for diagnosis of gynecologic cancer.Innate immunity in HIV-1 infection: epithelial and non-specific host factors of mucosal immunity- a workshop report.Neutrophils in ulcerative colitis: a review of selected biomarkers and their potential therapeutic implications.Physiopathological factors affecting the diagnostic value of serum HE4-test for gynecologic malignancies.Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract.Elafin (SKALP/Trappin-2/proteinase inhibitor-3) is produced by the cervix in pregnancy and cervicovaginal levels are diminished in bacterial vaginosis.
P2860
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P2860
The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The trappin gene family: prote ...... -terminal four-disulphide core
@ast
The trappin gene family: prote ...... -terminal four-disulphide core
@en
The trappin gene family: prote ...... -terminal four-disulphide core
@en-gb
The trappin gene family: prote ...... -terminal four-disulphide core
@nl
type
label
The trappin gene family: prote ...... -terminal four-disulphide core
@ast
The trappin gene family: prote ...... -terminal four-disulphide core
@en
The trappin gene family: prote ...... -terminal four-disulphide core
@en-gb
The trappin gene family: prote ...... -terminal four-disulphide core
@nl
prefLabel
The trappin gene family: prote ...... -terminal four-disulphide core
@ast
The trappin gene family: prote ...... -terminal four-disulphide core
@en
The trappin gene family: prote ...... -terminal four-disulphide core
@en-gb
The trappin gene family: prote ...... -terminal four-disulphide core
@nl
P2093
P2860
P356
P1433
P1476
The trappin gene family: prote ...... -terminal four-disulphide core
@en
P2093
P2860
P304
P356
10.1042/BJ3400569
P407
P478
340 ( Pt 3)
P577
1999-06-15T00:00:00Z