Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor - Wikidata - awgldk - TriplyDB

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

http://www.wikidata.org/entity/Q28269619

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Artificial ligand binding within the HIF2 PAS-B domain of the HIF2 transcription factor ARNT PAS-B has a fragile native state structure with an alternative -sheet register nearby in sequence space Principles of Ligand Binding within a Completely Buried Cavity in HIF2α PAS-B Identification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interaction Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor Allosteric inhibition of hypoxia inducible factor-2 with small molecules Protein dynamics of the HIF-2α PAS-B domain upon heterodimerization and ligand binding On the acquisition and analysis of microscale thermophoresis data.Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1α Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner.Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B Deletion of ARNT (Aryl hydrocarbon receptor nuclear translocator) in β-cells causes islet transplant failure with impaired β-cell function.Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia Molecular basis of coiled coil coactivator recruitment by the aryl hydrocarbon receptor nuclear translocator (ARNT).Coactivator recruitment: a new role for PAS domains in transcriptional regulation by the bHLH-PAS family.Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.Tripping the light fantastic: blue-light photoreceptors as examples of environmentally modulated protein-protein interactions.Intraplaque neovascularization as a novel therapeutic target in advanced atherosclerosis.MafG controls the hypoxic response of cells by accumulating HIF-1alpha in the nuclei.Unique and overlapping transcriptional roles of arylhydrocarbon receptor nuclear translocator (Arnt) and Arnt2 in xenobiotic and hypoxic responses.Low oxygen stimulates the intellect. Symposium on hypoxia and development, physiology and disease.Metabolic Regulation of T Cell Immunity.Ligand-induced perturbation of the HIF-2α:ARNT dimer dynamics.Critical role of the heme axial ligand, Met95, in locking catalysis of the phosphodiesterase from Escherichia coli (Ec DOS) toward Cyclic diGMP.

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P2860

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

http://www.wikidata.org/entity/Q28269619

description

2005 nî lūn-bûn

@nan

2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@ast

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@en

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@nl

type

label

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@ast

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@en

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@nl

prefLabel

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@ast

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@en

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

@en

P2093

Jinsong Yang

http://www.w3.org/2001/XMLSchema#string

Joseph A Garcia

http://www.w3.org/2001/XMLSchema#string

Kan Ding

http://www.w3.org/2001/XMLSchema#string

Lei Zhang

http://www.w3.org/2001/XMLSchema#string

Paul J A Erbel

http://www.w3.org/2001/XMLSchema#string

Richard K Bruick

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P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

A conserved family of prolyl-4-hydroxylases that modify HIF

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor.

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

P304

36047-54

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scholarly article

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10.1074/JBC.M501755200

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P433

43

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P478

280

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P50

Kevin H. Gardner

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2005-10-28T00:00:00Z

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P698

16129688

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P921