The kinetic factors that determine the affinity and selectivity for slow binding inhibition of human prostaglandin H synthase 1 and 2 by indomethacin and flurbiprofen
about
Role of Tyr348 in Tyr385 radical dynamics and cyclooxygenase inhibitor interactions in prostaglandin H synthase-2A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitorsStructural basis for certain naturally occurring bioflavonoids to function as reducing co-substrates of cyclooxygenase I and IIA Four-Point Screening Method for Assessing Molecular Mechanism of Action (MMOA) Identifies Tideglusib as a Time-Dependent Inhibitor of Trypanosoma brucei GSK3βIdentification and characterization of a cyclooxygenase-like enzyme from Entamoeba histolyticaSynthesis and kinetic analysis of some phosphonate analogs of cyclophostin as inhibitors of human acetylcholinesterase.A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirinPreclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.Influence of nonsteroidal anti-inflammatory drugs on aspirin's antiplatelet effects and suggestion of the most suitable time for administration of both agents without resulting in interaction.Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents.On the different experimental manifestations of two-state 'induced-fit' binding of drugs to their cellular targetsIn Silico Screening of Nonsteroidal Anti-Inflammatory Drugs and Their Combined Action on Prostaglandin H Synthase-1.Conformational adaptation in drug-target interactions and residence time.Kinetic basis for selective inhibition of cyclo-oxygenasesRat hormone sensitive lipase inhibition by cyclipostins and their analogs.Detergents profoundly affect inhibitor potencies against both cyclo-oxygenase isoforms.The dynamics of prostaglandin H synthases. Studies with prostaglandin h synthase 2 Y355F unmask mechanisms of time-dependent inhibition and allosteric activation.Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site.Role of expression of prostaglandin synthases 1 and 2 and leukotriene C4 synthase in aspirin-intolerant asthma: a theoretical study.Comparison of structural stabilities of prostaglandin H synthase-1 and -2.Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry.
P2860
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P2860
The kinetic factors that determine the affinity and selectivity for slow binding inhibition of human prostaglandin H synthase 1 and 2 by indomethacin and flurbiprofen
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The kinetic factors that deter ...... indomethacin and flurbiprofen
@ast
The kinetic factors that deter ...... indomethacin and flurbiprofen
@en
The kinetic factors that deter ...... indomethacin and flurbiprofen
@nl
type
label
The kinetic factors that deter ...... indomethacin and flurbiprofen
@ast
The kinetic factors that deter ...... indomethacin and flurbiprofen
@en
The kinetic factors that deter ...... indomethacin and flurbiprofen
@nl
prefLabel
The kinetic factors that deter ...... indomethacin and flurbiprofen
@ast
The kinetic factors that deter ...... indomethacin and flurbiprofen
@en
The kinetic factors that deter ...... indomethacin and flurbiprofen
@nl
P2093
P2860
P356
P1476
The kinetic factors that deter ...... indomethacin and flurbiprofen
@en
P2093
P2860
P304
P356
10.1074/JBC.271.7.3548
P407
P577
1996-02-16T00:00:00Z