The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation
about
USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activityThe ubiquitin-specific protease USP28 is required for MYC stabilityThe E3 ligase TRAF6 regulates Akt ubiquitination and activationUbiquitin ligase ARF-BP1/Mule modulates base excision repairInhibition of c-Myc activity by ribosomal protein L11Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentThe role of MIZ-1 in MYC-dependent tumorigenesisA Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination ActivitiesNovel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.Trial Watch: Proteasomal inhibitors for anticancer therapyDivorcing ARF and p53: an unsettled caseThe Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA bindingWwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent mannerA ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growthp53 ubiquitination: Mdm2 and beyondMYC on the path to cancerHECT E3s and human disease.Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1Analysis of Myc-induced histone modifications on target chromatin.Homeostatic defects in B cells deficient in the E3 ubiquitin ligase ARF-BP1 are restored by enhanced expression of MYCE3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation.Role of Pirh2 in mediating the regulation of p53 and c-Myc.HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.Limiting the power of p53 through the ubiquitin proteasome pathway.Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.Replication licensing and the DNA damage checkpoint.UBE1L2, a novel E1 enzyme specific for ubiquitin.Polymorphism of ZBTB17 gene is associated with idiopathic dilated cardiomyopathy: a case control study in a Han Chinese population.A novel HECT-type E3 ubiquitin protein ligase NEDL1 enhances the p53-mediated apoptotic cell death in its catalytic activity-independent manner.Miz-1 regulates translation of Trp53 via ribosomal protein L22 in cells undergoing V(D)J recombinationRegulation of Akt signaling activation by ubiquitination.Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.Development of inhibitors in the ubiquitination cascade.Role of STRAP in regulating GSK3β function and Notch3 stabilization.Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-MycSUMOylation of Myc-family proteinsTumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligaseAutoregulatory suppression of c-Myc by miR-185-3p.
P2860
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P2860
The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@ast
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@en
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@nl
type
label
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@ast
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@en
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@nl
prefLabel
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@ast
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@en
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@nl
P2093
P50
P3181
P1433
P1476
The ubiquitin ligase HectH9 re ...... l for tumor cell proliferation
@en
P2093
Andreas Hock
Esther Hulleman
Federica Marinoni
Maria Capra
Micaela Quarto
Nikita Popov
Rudi Beier
Sandra Bernard
Sovana Adhikary
Stephan Goettig
P304
P3181
P356
10.1016/J.CELL.2005.08.016
P407
P577
2005-11-04T00:00:00Z