about
Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assaysA first-in-human, phase 1, dose-escalation study of dinaciclib, a novel cyclin-dependent kinase inhibitor, administered weekly in subjects with advanced malignanciesC10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancerPlk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppressionDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerRASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosisSmall-molecule inhibitors of the Myc oncoproteinFluorescent peptide biosensor for probing the relative abundance of cyclin-dependent kinases in living cellsBriefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for CatalysisCDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.Transcriptional control of mitosis: deregulation and cancerNuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinasesRational methods for the selection of diverse screening compoundsStructural and functional characterization of the protein kinase Mps1 in Arabidopsis thalianaThe NIMA-family kinase Nek3 regulates microtubule acetylation in neuronsTargeting cancer with small molecule kinase inhibitorsAnticancer effect of Tamarix gallica extracts on human colon cancer cells involves Erk1/2 and p38 action on G2/M cell cycle arrest.In Vitro Antiproliferative Effect of Arthrocnemum indicum Extracts on Caco-2 Cancer Cells through Cell Cycle Control and Related Phenol LC-TOF-MS Identification.The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpointExplorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis.Phosphorylation by Cdk1 increases the binding of Eg5 to microtubules in vitro and in Xenopus egg extract spindlesGenetic interactions between the Drosophila tumor suppressor gene ept and the stat92E transcription factor.Structural interrogation of phosphoproteome identified by mass spectrometry reveals allowed and disallowed regions of phosphoconformation.Functional classification of proteins based on projection of amino acid sequences: application for prediction of protein kinase substrates.Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma.CARP is a potential tumor suppressor in gastric carcinoma and a single-nucleotide polymorphism in CARP gene might increase the risk of gastric carcinoma.Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.Polyisoprenylated methylated protein methyl esterase as a putative drug target for androgen-insensitive prostate cancer.Rab11-FIP3 is a cell cycle-regulated phosphoproteinCell Cycle Deregulation in Ewing's Sarcoma PathogenesisComplementary Fe(3+)- and Ti(4+)-immobilized metal ion affinity chromatography for purification of acidic and basic phosphopeptides.Telomere dysfunction suppresses multiple endocrine neoplasia in mice.Proteomic analysis of the human cyclin-dependent kinase family reveals a novel CDK5 complex involved in cell growth and migrationDe-regulation of JNK and JAK/STAT signaling in ESCRT-II mutant tissues cooperatively contributes to neoplastic tumorigenesis.Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy.Mastl kinase, a promising therapeutic target, promotes cancer recurrence.STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells.Apoptotic effects of genistein, biochanin-A and apigenin on LNCaP and PC-3 cells by p21 through transcriptional inhibition of polo-like kinase-1.A MEK-independent role for CRAF in mitosis and tumor progression.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Cell cycle kinases in cancer
@ast
Cell cycle kinases in cancer
@en
Cell cycle kinases in cancer
@nl
type
label
Cell cycle kinases in cancer
@ast
Cell cycle kinases in cancer
@en
Cell cycle kinases in cancer
@nl
prefLabel
Cell cycle kinases in cancer
@ast
Cell cycle kinases in cancer
@en
Cell cycle kinases in cancer
@nl
P3181
P1476
Cell cycle kinases in cancer
@en
P2093
Mariano Barbacid
P3181
P356
10.1016/J.GDE.2006.12.008
P407
P577
2007-02-01T00:00:00Z