Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
about
Short-term calorie restriction in male mice feminizes gene expression and alters key regulators of conserved aging regulatory pathwaysDietary restriction depends on nutrient composition to extend chronological lifespan in budding yeast Saccharomyces cerevisiaeInhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's diseaseSIRT1 negatively regulates the mammalian target of rapamycinRecent developments in yeast agingLife span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9Increased life span due to calorie restriction in respiratory-deficient yeastExtension of chronological life span in yeast by decreased TOR pathway signalingThe TOR pathway comes of ageDietary interventions to extend life span and health span based on calorie restrictionNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismRapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevityExtending healthy life span--from yeast to humansLessons on longevity from budding yeastmTOR is a key modulator of ageing and age-related diseaseChemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processesAn emerging role for TOR signaling in mammalian tissue and stem cell physiologyAging as an event of proteostasis collapseReduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expressionReplicative and chronological aging in Saccharomyces cerevisiae.mTOR: from growth signal integration to cancer, diabetes and ageingMolecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.mTOR signaling in growth control and diseaseThe neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodiesRapamycin fed late in life extends lifespan in genetically heterogeneous miceRapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instabilitySIRT6 in DNA repair, metabolism and ageingThe Epigenetic Pathways to Ribosomal DNA SilencingMammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain FunctionFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesThe crucial impact of lysosomes in aging and longevityInhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and BeyondThe short-lived African turquoise killifish: an emerging experimental model for ageingLive strong and prosper: the importance of skeletal muscle strength for healthy ageingThe role of the ribosome in the regulation of longevity and lifespan extensionLong live FOXO: unraveling the role of FOXO proteins in aging and longevityBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesSirtuin 1 and aging theory for chronic obstructive pulmonary diseaseThe controversial world of sirtuinsFOXO transcription factors: key regulators of cellular quality control
P2860
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P2860
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@ast
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@en
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@nl
type
label
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@ast
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@en
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@nl
prefLabel
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@ast
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@en
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@nl
P2093
P3181
P356
P1433
P1476
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
@en
P2093
Brian K Kennedy
Emily O Kerr
Eric A Westman
Kathryn T Kirkland
Kristan K Steffen
R Wilson Powers
Stanley Fields
P304
P3181
P356
10.1126/SCIENCE.1115535
P407
P577
2005-11-18T00:00:00Z