Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells
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Controversies in the Mechanism of Total Parenteral Nutrition Induced PathologyThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsADAM-17: the enzyme that does it all.Differential regulation of EGFR-MAPK signaling by deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA) in colon cancerBile acid dysregulation, gut dysbiosis, and gastrointestinal cancer.The bile acid membrane receptor TGR5: a valuable metabolic target.Bile acids regulate intestinal cell proliferation by modulating EGFR and FXR signaling.Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs.The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation.Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling.The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.Membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemiaGPBA: a GPCR for bile acids and an emerging therapeutic target for disorders of digestion and sensation.Bile salt receptor TGR5 is highly expressed in esophageal adenocarcinoma and precancerous lesions with significantly worse overall survival and gender differences.The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines.Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis.Metabolic surgery-principles and current concepts.Patented TGR5 modulators: a review (2006 - present).The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders.The bile acid TGR5 membrane receptor: from basic research to clinical application.Neuro-humoral signalling by bile acids and the TGR5 receptor in the gastrointestinal tract.TGR5 in inflammation and cardiovascular disease.TGR5: pathogenetic role and/or therapeutic target in fibrosing cholangitis?Formulations of deoxycholic for therapy: a patent review (2011 - 2014).Therapeutic potential of Takeda-G-protein-receptor-5 (TGR5) agonists. Hope or hype?TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro.Activation of the bile acid receptor TGR5 enhances LPS-induced inflammatory responses in a human monocytic cell line.Bile acid at low pH reduces squamous differentiation and activates EGFR signaling in esophageal squamous cells in 3-D culture.TGR5 in the Cholangiociliopathies.Bile acids induce cdx2 expression through the farnesoid x receptor in gastric epithelial cells.Bile Salts at Low pH Cause Dilation of Intercellular Spaces in In Vitro Stratified Primary Esophageal Cells, Possibly by Modulating Wnt Signaling.Prognostic value of ADAM17 in human gastric cancer.Preserved Gut Microbial Diversity Accompanies Upregulation of TGR5 and Hepatobiliary Transporters in Bile Acid-Treated Animals Receiving Parenteral Nutrition.Oleanolic Acid Improves Gut Atrophy Induced by Parenteral Nutrition.ADAM17 is overexpressed in non-small cell lung cancer and its expression correlates with poor patient survival.Activation of FXR promotes intestinal metaplasia of gastric cells via SHP-dependent upregulation of the expression of CDX2.Role of the Gut⁻Liver Axis in Driving Parenteral Nutrition-Associated Injury
P2860
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P2860
Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@ast
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@en
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@nl
type
label
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@ast
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@en
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@nl
prefLabel
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@ast
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@en
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@nl
P2093
P3181
P1476
Involvement of membrane-type b ...... ses in gastric carcinoma cells
@en
P2093
Hirohide Ohnishi
Hirosato Mashima
Hiroshi Yasuda
Kazuaki Inoue
Makoto Yoshiba
Shuko Hirata
P3181
P356
10.1016/J.BBRC.2006.12.168
P407
P577
2007-03-02T00:00:00Z