The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation.
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Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cellsReview of experimental animal models of biliary acute pancreatitis and recent advances in basic researchBile acid metabolism and signalingBile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rateTreating Obesity and Metabolic Syndrome with Fecal Microbiota TransplantationDiacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytesBile acid signaling in metabolic disease and drug therapyUrsodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytesEmpirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation MechanismsDaily Eating Patterns and Their Impact on Health and Disease.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsInvestigation of triamterene as an inhibitor of the TGR5 receptor: identification in cells and animals.Fasting serum taurine-conjugated bile acids are elevated in type 2 diabetes and do not change with intensification of insulinThe artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice.A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice.Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitusTGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading.PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis.The heteromeric organic solute transporter, OSTα-OSTβ/SLC51: a transporter for steroid-derived moleculesMechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acidThrombin inhibition with dabigatran protects against high-fat diet-induced fatty liver disease in miceSodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters.Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer.INTRACELLULAR SIGNALING BY BILE ACIDS.Highly lipophilic 3-epi-betulinic acid derivatives as potent and selective TGR5 agonists with improved cellular efficacy.Potency of individual bile acids to regulate bile acid synthesis and transport genes in primary human hepatocyte cultures.TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translationBariatric surgery: prevalence, predictors, and mechanisms of diabetes remission.Metabolic effects of cholecystectomy: gallbladder ablation increases basal metabolic rate through G-protein coupled bile acid receptor Gpbar1-dependent mechanisms in mice.Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease.Changes in bile acids, FGF-19 and sterol absorption in response to bile salt hydrolase active L. reuteri NCIMB 30242.Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method.Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration.The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling PathwayLithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor.Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cellsHydrophobic bile acids relax rat detrusor contraction via inhibiting the opening of the Na⁺/Ca²⁺ exchanger.Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM ratsThe solute carrier family 10 (SLC10): beyond bile acid transport
P2860
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P2860
The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The bile acid membrane recepto ...... n metabolism and inflammation.
@en
type
label
The bile acid membrane recepto ...... n metabolism and inflammation.
@en
prefLabel
The bile acid membrane recepto ...... n metabolism and inflammation.
@en
P2093
P2860
P1476
The bile acid membrane recepto ...... n metabolism and inflammation.
@en
P2093
Lilia G Noriega
Mitsunori Nomura
Thijs W H Pols
P2860
P304
P356
10.1016/J.JHEP.2010.12.004
P577
2010-12-09T00:00:00Z