Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria - Wikidata - awgldk - TriplyDB

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

http://www.wikidata.org/entity/Q28285347

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Mitochondria, calcium and cell death: a deadly triad in neurodegeneration Mitochondria-associated ER membranes and Alzheimer disease Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease Mitochondrial oxidative stress in aging and healthspan Regulation of distinct pools of amyloid β-protein by multiple cellular proteases Two isoforms of PSAP/MTCH1 share two proapoptotic domains and multiple internal signals for import into the mitochondrial outer membrane A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine Pathogenesis of Alzheimer's disease Domain organization of long signal peptides of single-pass integral membrane proteins reveals multiple functional capacity.Synaptic and endosomal localization of active gamma-secretase in rat brain.Convergence of pathology in dementia with Lewy bodies and Alzheimer's disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease.Superoxide anion, uncoupling proteins and Alzheimer's disease.Convergence of amyloid-beta and tau pathologies on mitochondria in vivo.A functional role for ADAM10 in human immunodeficiency virus type-1 replication The neurodegenerative mitochondriopathies.Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.Gamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase A mitochondrial etiology of Alzheimer and Parkinson disease Identification of novel γ-secretase-associated proteins in detergent-resistant membranes from brain.Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells.The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging Amyloid accumulation is a late event in sporadic Alzheimer's disease-like pathology in nontransgenic rats.Oxidative damage and cognitive dysfunction: antioxidant treatments to promote healthy brain aging Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice Mitochondrial medicine for aging and neurodegenerative diseases Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.Mitochondrial Ca(2+) and neurodegeneration Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid.The role of mitochondria in inherited neurodegenerative diseases.Mitochondria in neurodegeneration.The mitochondrial permeability transition in neurologic disease p120-catenin is a key component of the cadherin-gamma-secretase supercomplex.Structural studies of the transmembrane C-terminal domain of the amyloid precursor protein (APP): does APP function as a cholesterol sensor?Amyloid precursor protein and mitochondrial dysfunction in Alzheimer's disease.Pathogenic role of mitochondrial [correction of mitochondral] amyloid-beta peptide.Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptors Mitochondria in neuroplasticity and neurological disorders.Prostaglandin I2 upregulates the expression of anterior pharynx-defective-1α and anterior pharynx-defective-1β in amyloid precursor protein/presenilin 1 transgenic mice.

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P2860

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

http://www.wikidata.org/entity/Q28285347

description

2004 nî lūn-bûn

@nan

2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

@zh-hk

2004年論文

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2004年論文

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2004年论文

@wuu

name

Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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type

label

Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

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Journal of Biological Chemistry

P1476

Nicastrin, presenilin, APH-1, ...... tase complexes in mitochondria

@en

P2093

Akira Ito

http://www.w3.org/2001/XMLSchema#string

Camilla A Hansson

http://www.w3.org/2001/XMLSchema#string

Camilla Nilsberth

http://www.w3.org/2001/XMLSchema#string

Johan Thyberg

http://www.w3.org/2001/XMLSchema#string

Lars O Tjernberg

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Maria Ankarcrona

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Mark R Farmery

http://www.w3.org/2001/XMLSchema#string

Richard F Cowburn

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Sharon E Pursglove

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Susanne Frykman

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51654-60

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scholarly article

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4812567

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10.1074/JBC.M404500200

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49

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279

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2004-12-03T00:00:00Z

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15456764

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