Synaptic and endosomal localization of active gamma-secretase in rat brain.
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Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid betaTrafficking and proteolytic processing of APPγ-secretase binding sites in aged and Alzheimer's disease human cerebrum: the choroid plexus as a putative origin of CSF AβCentral angiotensin II stimulation promotes β amyloid production in Sprague Dawley rats.Amyloid precursor protein is trafficked and secreted via synaptic vesiclesModeling presenilin-dependent familial Alzheimer's disease: emphasis on presenilin substrate-mediated signaling and synaptic function.Gamma-secretase-dependent amyloid-beta is increased in Niemann-Pick type C: a cross-sectional studyVisualizing active enzyme complexes using a photoreactive inhibitor for proximity ligation--application on γ-secretase.Sorting nexin 17 regulates ApoER2 recycling and reelin signalingAD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assemblySynaptotagmins interact with APP and promote Aβ generation.Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex.Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons.Impaired endolysosomal function disrupts Notch signalling in optic nerve astrocytesEffects of grape seed proanthocyanidin on Alzheimer's disease in vitro and in vivoPhenserine efficacy in Alzheimer's disease.UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport.The very many faces of presenilins and the γ-secretase complex.G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses.Synapses in neurodegenerative diseases.A Translational Systems Pharmacology Model for Aβ Kinetics in Mouse, Monkey, and Human.p75 neurotrophin receptor interacts with and promotes BACE1 localization in endosomes aggravating amyloidogenesis.Pre-synaptic localization of the γ-secretase-inhibiting protein p24α2 in the mammalian brain.Effects of aluminium on β-amyloid (1-42) and secretases (APP-cleaving enzymes) in rat brain.Regulated intramembrane proteolysis: emergent role in cell signalling pathways.
P2860
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P248
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P2860
Synaptic and endosomal localization of active gamma-secretase in rat brain.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@ast
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@en
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@nl
type
label
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@ast
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@en
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@nl
prefLabel
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@ast
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@en
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@nl
P2093
P2860
P1433
P1476
Synaptic and endosomal localization of active gamma-secretase in rat brain.
@en
P2093
Homira Behbahani
Jarmila Nahalkova
Jenny Frånberg
Ji-Yeun Hur
Lars O Tjernberg
Mikio Aoki
Susanne Frykman
P2860
P356
10.1371/JOURNAL.PONE.0008948
P407
P577
2010-01-28T00:00:00Z