The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals - Wikidata - awgldk - TriplyDB

The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

http://www.wikidata.org/entity/Q28292543

about

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity Understanding the genetic and molecular pathogenesis of Friedreich's ataxia through animal and cellular models The role of mitochondria in cellular iron-sulfur protein biogenesis: mechanisms, connected processes, and diseases Iron and cancer: more ore to be mined.Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated with Friedreich's ataxia.The deca-GX3 proteins Yae1-Lto1 function as adaptors recruiting the ABC protein Rli1 for iron-sulfur cluster insertion.DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster.A gene expression phenotype in lymphocytes from Friedreich ataxia patients.Neurodegeneration in Friedreich's ataxia: from defective frataxin to oxidative stress Crosstalk between MSH2-MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair.Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts Deep sequencing of mitochondrial genomes reveals increased mutation load in Friedreich's ataxia.Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells.

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P2860

The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

http://www.wikidata.org/entity/Q28292543

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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type

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

@ast

The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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Biochemical Journal

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The Friedreich's ataxia protei ...... air in prokaryotes and mammals

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Anja Voigt

http://www.w3.org/2001/XMLSchema#string

Bernd Epe

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Carina Reiche

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Gunnar Drewes

http://www.w3.org/2001/XMLSchema#string

Markus Fusser

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Pablo Steinberg

http://www.w3.org/2001/XMLSchema#string

Tim J Schulz

http://www.w3.org/2001/XMLSchema#string

Urte Blume

http://www.w3.org/2001/XMLSchema#string

P2860

Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

An improved bacterial test system for the detection and classification of mutagens and carcinogens

Crystal structure of human frataxin

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

The DNA repair helicases XPD and FancJ have essential iron-sulfur domains.

An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.

Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity.

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III. Direct identification of Lys-212 as the active nucleophilic residue

Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited

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165-72

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scholarly article

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814128

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10.1042/BJ20101116

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1

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432

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Hansruedi Glatt

René Thierbach

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2010-11-15T00:00:00Z

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46157546

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20819074

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