An architectural framework that may lie at the core of the postsynaptic density
about
Modulation of neuronal signal transduction and memory formation by synaptic zincImportance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapsesMutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disordersThe postsynaptic density proteins Homer and Shank form a polymeric network structureContribution of SHANK3 mutations to autism spectrum disorderAbelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formationComposition of the synaptic PSD-95 complexCellular and synaptic network defects in autismCNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signalingRegulation of clathrin adaptor function in endocytosis: novel role for the SAM domain.Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domainTandem SAM Domain Structure of Human Caskin1: A Presynaptic, Self-Assembling Scaffold for CASKCharacterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3Multiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motifPhase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic PlasticitySAM domain-dependent activity of PfTKL3, an essential tyrosine kinase-like kinase of the human malaria parasite Plasmodium falciparumA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Discovery of Rare Mutations in Autism: Elucidating Neurodevelopmental MechanismsAutistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletionDevelopment of novel Zn2+ loaded nanoparticles designed for cell-type targeted drug release in CNS neurons: in vitro evidencesProSAP-interacting protein 1 (ProSAPiP1), a novel protein of the postsynaptic density that links the spine-associated Rap-Gap (SPAR) to the scaffolding protein ProSAP2/Shank3Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathwaysDifferential distribution of Shank and GKAP at the postsynaptic densityPostsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to HomerShank1 mRNA: dendritic transport by kinesin and translational control by the 5'untranslated regionExcess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disabilityStriatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism.SHANK proteins: roles at the synapse and in autism spectrum disorder.Expression of SHANK3 in the Temporal Neocortex of Patients with Intractable Temporal Epilepsy and Epilepsy Rat Models.Phelan-McDermid Syndrome and SHANK3: Implications for Treatment.Molecular handoffs in nitrergic neurotransmissionAssociation study of SHANK3 gene polymorphisms with autism in Chinese Han population.A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.Minimal functional sites allow a classification of zinc sites in proteins.SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism.Studying autism in rodent models: reconciling endophenotypes with comorbiditiesReduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant miceOrganization of the core structure of the postsynaptic densityStructural plasticity with preserved topology in the postsynaptic protein network.
P2860
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P2860
An architectural framework that may lie at the core of the postsynaptic density
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
An architectural framework that may lie at the core of the postsynaptic density
@ast
An architectural framework that may lie at the core of the postsynaptic density
@en
An architectural framework that may lie at the core of the postsynaptic density
@nl
type
label
An architectural framework that may lie at the core of the postsynaptic density
@ast
An architectural framework that may lie at the core of the postsynaptic density
@en
An architectural framework that may lie at the core of the postsynaptic density
@nl
prefLabel
An architectural framework that may lie at the core of the postsynaptic density
@ast
An architectural framework that may lie at the core of the postsynaptic density
@en
An architectural framework that may lie at the core of the postsynaptic density
@nl
P2093
P3181
P356
P1433
P1476
An architectural framework that may lie at the core of the postsynaptic density
@en
P2093
Bianca Vaida
Danielle Salyer
James U Bowie
Mari Gingery
Marisa K Baron
Michael R Sawaya
Salem Faham
Tobias M Boeckers
P3181
P356
10.1126/SCIENCE.1118995
P407
P577
2006-01-27T00:00:00Z