Network pharmacology: the next paradigm in drug discovery
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Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug developmentGenome-scale screening of drug-target associations relevant to Ki using a chemogenomics approachTRIP database 2.0: a manually curated information hub for accessing TRP channel interaction networkHow drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionAnalysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinomaParallel visualization of multiple protein complexes in individual cells in tumor tissueDeveloping dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxideGenome-environment interactions that modulate aging: powerful targets for drug discoveryUpdate of TTD: Therapeutic Target DatabaseChemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasisDrug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening MethodologiesMultiple Targeting Approaches on Histamine H3 Receptor AntagonistsOne for All? Hitting Multiple Alzheimer's Disease Targets with One DrugNavigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's DiseaseSystems psychopharmacology: A network approach to developing novel therapiesBreaking the Spell: Combating Multidrug Resistant 'Superbugs'Biomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory scienceSystematic analysis of the associations between adverse drug reactions and pathwaysConstellation pharmacology: a new paradigm for drug discoveryNetwork-based approaches in drug discovery and early developmentBeyond modules and hubs: the potential of gene coexpression networks for investigating molecular mechanisms of complex brain disordersCholinergic modulation by opioid receptor ligands: potential application to Alzheimer's diseaseAre cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic reviewStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewSystems genetics for drug target discoveryA metabolic network approach for the identification and prioritization of antimicrobial drug targetsThree-dimensional cell culture systems and their applications in drug discovery and cell-based biosensorsChem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology dataShifting from the single to the multitarget paradigm in drug discoveryMetabolomics and systems pharmacology: why and how to model the human metabolic network for drug discoveryFenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent modelsHarvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactomeBifunctional Lipocalin Ameliorates Murine Immune Complex-induced Acute Lung InjurySystems biology approaches for advancing the discovery of effective drug combinationsA multi-label approach to target prediction taking ligand promiscuity into accountQuantitative modeling of dose–response and drug combination based on pathway networkA fast topological analysis algorithm for large-scale similarity evaluations of ligands and binding pocketsBotanicals and Their Bioactive Phytochemicals for Women's HealthA Dormant Microbial Component in the Development of PreeclampsiaIncorporating Natural Products, Pharmaceutical Drugs, Self-Care and Digital/Mobile Health Technologies into Molecular-Behavioral Combination Therapies for Chronic Diseases
P2860
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P2860
Network pharmacology: the next paradigm in drug discovery
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Network pharmacology: the next paradigm in drug discovery
@ast
Network pharmacology: the next paradigm in drug discovery
@en
Network pharmacology: the next paradigm in drug discovery
@nl
type
label
Network pharmacology: the next paradigm in drug discovery
@ast
Network pharmacology: the next paradigm in drug discovery
@en
Network pharmacology: the next paradigm in drug discovery
@nl
prefLabel
Network pharmacology: the next paradigm in drug discovery
@ast
Network pharmacology: the next paradigm in drug discovery
@en
Network pharmacology: the next paradigm in drug discovery
@nl
P3181
P356
P1476
Network pharmacology: the next paradigm in drug discovery
@en
P2093
Andrew L Hopkins
P2888
P304
P3181
P356
10.1038/NCHEMBIO.118
P407
P577
2008-11-01T00:00:00Z