Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure. - Wikidata - awgldk - TriplyDB

Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.

Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.

http://www.wikidata.org/entity/Q36720833

about

Connexins and pannexins in liver damage Connexin and pannexin signaling in gastrointestinal and liver disease Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.Synchronized necrotic death of attached hepatocytes mediated via gap junctions.Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.Purinergic signalling during sterile liver injury.Dimethyl sulfoxide induces both direct and indirect tau hyperphosphorylation.Different gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells.A novel TXNIP-based mechanism for Cx43-mediated regulation of oxidative drug injury A new high-throughput screening-compatible gap junctional intercellular communication assay Increased liver-specific proteins in circulating extracellular vesicles as potential biomarkers for drug- and alcohol-induced liver injury.Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription.Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity.Macrophage Migration Inhibitor Factor Upregulates MCP-1 Expression in an Autocrine Manner in Hepatocytes during Acute Mouse Liver Injury.Connexin32: a mediator of acetaminophen-induced liver injury?Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells.Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver.Gap-junction-mediated cell-to-cell communication.Liver repopulation and regeneration: new approaches to old questions.Assembly of human organs from stem cells to study liver disease.Connexin and pannexin (hemi)channels in the liver.Calcium signaling and the secretory activity of bile duct epithelia.GJIC Enhances the phototoxicity of photofrin-mediated photodynamic treatment by the mechanisms related with ROS and Calcium pathways.The role of gap junctions in inflammatory and neoplastic disorders (Review).Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.Connexin-based signaling and drug-induced hepatotoxicity.Multicellular assembly and light-regulation of cell-cell communication by conjugated polymer materials.Connexin 32 and connexin 43 are involved in lineage restriction of hepatic progenitor cells to hepatocytes.2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice.Connexin hemichannel inhibition reduces acetaminophen-induced liver injury in mice.Prevention of cisplatin-induced ototoxicity by the inhibition of gap junctional intercellular communication in auditory cells.Therapeutic efficacy of Wuzhi tablet (Schisandra sphenanthera Extract) on acetaminophen-induced hepatotoxicity through a mechanism distinct from N-acetylcysteine.

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Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.

http://www.wikidata.org/entity/Q36720833

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2012 nî lūn-bûn

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Gap junction inhibition preven ...... and fulminant hepatic failure.

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Gap junction inhibition preven ...... and fulminant hepatic failure.

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Gap junction inhibition preven ...... and fulminant hepatic failure.

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Nature Biotechnology

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Gap junction inhibition preven ...... and fulminant hepatic failure.

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P2093

Antonia Vitalo

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Arvin Iracheta-Vellve

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Biju Parekkadan

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Jack M Milwid

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Kevin R King

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Martin L Yarmush

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Matthew Li

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Rohit Jindal

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Stefan Bohr

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Suraj J Patel

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P2860

Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure.

Mechanisms of hepatotoxicity

Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin

DNA-triggered innate immune responses are propagated by gap junction communication

Intrinsic versus idiosyncratic drug-induced hepatotoxicity--two villains or one?

Mechanisms of drug-induced liver injury: from bedside to bench.

Drug-induced hepatotoxicity.

Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: the importance of reporting suspected reactions.

Drug-related hepatotoxicity.

Acetaminophen hepatotoxicity and acute liver failure.

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179-183

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10.1038/NBT.2089

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2

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30

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2012-01-15T00:00:00Z

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221754476

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22252509

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3609650

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