Crystal structure of a soluble CD28-Fab complex - Wikidata - awgldk - TriplyDB

Crystal structure of a soluble CD28-Fab complex

Crystal structure of a soluble CD28-Fab complex

http://www.wikidata.org/entity/Q28306324

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The B7 family of immune-regulatory ligands CD28 co-stimulation in T-cell homeostasis: a recent perspective Binding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shock Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2 Structure of Signal-regulatory Protein : A LINK TO ANTIGEN RECEPTOR EVOLUTION Domain Metastability: A Molecular Basis for Immunoglobulin Deposition?Structural and Functional Studies of Igαβ and Its Assembly with the B Cell Antigen Receptor Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering Molecular Insights into γδ T Cell Costimulation by an Anti-JAML Antibody Structure and Interactions of the Human Programmed Cell Death 1 Receptor T Cell Receptors are Structures Capable of Initiating Signaling in the Absence of Large Conformational Rearrangements Controlling NF-kappaB activation in T cells by costimulatory receptors Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse An enigmatic tail of CD28 signaling.Different cell surface oligomeric states of B7-1 and B7-2: implications for signaling.Sequence, structure, function, immunity: structural genomics of costimulation.Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex.Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases.The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.T cell receptor signaling can directly enhance the avidity of CD28 ligand binding.A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats Anti-CD28 Antibody-Initiated Cytokine Storm in Canines.Granzyme B- and Fas ligand-mediated cytotoxic function induced by mitogenic CD28 stimulation of human memory CD4+ T cells The interchain disulfide linkage is not a prerequisite but enhances CD28 costimulatory function Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant.Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis.The potential role of fowlpox virus in rational vaccine design.The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor.An engineered lipocalin specific for CTLA-4 reveals a combining site with structural and conformational features similar to antibodies.CD28: direct and critical receptor for superantigen toxins Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor.Superantigens hyperinduce inflammatory cytokines by enhancing the B7-2/CD28 costimulatory receptor interaction.Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells.Bacterial superantigen toxins induce a lethal cytokine storm by enhancing B7-2/CD28 costimulatory receptor engagement, a critical immune checkpoint.CD28 and IL-4: two heavyweights controlling the balance between immunity and inflammation.Non-catalytic tyrosine-phosphorylated receptors.Functional analysis of acquired CD28 mutations identified in cutaneous T cell lymphoma.Costimulation of IL-2 Production through CD28 Is Dependent on the Size of Its Ligand.

P2860

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P2860

Crystal structure of a soluble CD28-Fab complex

http://www.wikidata.org/entity/Q28306324

description

2005 nî lūn-bûn

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2005 թուականի Մարտին հրատարակուած գիտական յօդուած

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2005 թվականի մարտին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Crystal structure of a soluble CD28-Fab complex

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Crystal structure of a soluble CD28-Fab complex

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Crystal structure of a soluble CD28-Fab complex

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type

label

Crystal structure of a soluble CD28-Fab complex

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Crystal structure of a soluble CD28-Fab complex

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Crystal structure of a soluble CD28-Fab complex

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prefLabel

Crystal structure of a soluble CD28-Fab complex

@ast

Crystal structure of a soluble CD28-Fab complex

@en

Crystal structure of a soluble CD28-Fab complex

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P1433

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P1433

Nature Immunology

P1476

Crystal structure of a soluble CD28-Fab complex

@en

P2093

Björn Walse

http://www.w3.org/2001/XMLSchema#string

Chao Yu

http://www.w3.org/2001/XMLSchema#string

Cheryl Vowles

http://www.w3.org/2001/XMLSchema#string

Edward J Evans

http://www.w3.org/2001/XMLSchema#string

Janet A Fennelly

http://www.w3.org/2001/XMLSchema#string

Poul Sørensen

http://www.w3.org/2001/XMLSchema#string

Raquel Manso-Sancho

http://www.w3.org/2001/XMLSchema#string

Robert M Esnouf

http://www.w3.org/2001/XMLSchema#string

Simon J Davis

http://www.w3.org/2001/XMLSchema#string

Thomas Hanke

http://www.w3.org/2001/XMLSchema#string

P2860

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Structural basis for co-stimulation by the human CTLA-4/B7-2 complex

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors

Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

Structure and dimerization of a soluble form of B7-1

P304

271-279

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scholarly article

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10.1038/NI1170

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P407

P433

3

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P478

6

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P50

David Ian Stuart

Robert J Gilbert

P577

2005-02-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8036837

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P698

15696168

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P921

crystal structure