Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
about
Artemisinin biosynthesis and its regulatory enzymes: Progress and perspectiveRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesAntimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma CareRecent progress of research on medicinal mushrooms, foods, and other herbal products used in traditional Chinese medicineMolecular biology of cantharidin in cancer cellsArtemisinin and Its Derivatives as a Repurposing Anticancer Agent: What Else Do We Need to Do?DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinomaArtesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cellsHeme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation targetAn artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activitiesIsolation and characterization of AaWRKY1, an Artemisia annua transcription factor that regulates the amorpha-4,11-diene synthase gene, a key gene of artemisinin biosynthesis.The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells.Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancerHypoxia-selective antitumor agents: norsesterterpene peroxides from the marine sponge Diacarnus levii preferentially suppress the growth of tumor cells under hypoxic conditions.Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signaling.Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-κB pathway in microglia cells.Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cellsType 2C phosphatase 1 of Artemisia annua L. is a negative regulator of ABA signaling.Self-assembled targeted nanoparticles based on transferrin-modified eight-arm-polyethylene glycol-dihydroartemisinin conjugate.The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers.Overexpression of the Artemisia orthologue of ABA receptor, AaPYL9, enhances ABA sensitivity and improves artemisinin content in Artemisia annua L.Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species productionRedox platforms in cancer drug discovery and development.Synergistic induction of apoptosis in A549 cells by dihydroartemisinin and gemcitabine.Phospho-TCTP as a therapeutic target of Dihydroartemisinin for aggressive breast cancer cells.Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety.Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapyCurrent advances in detection and treatment of babesiosisFarnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives.Repurposing the anti-malarial drug artesunate as a novel therapeutic agent for metastatic renal cell carcinoma due to its attenuation of tumor growth, metastasis, and angiogenesis.Diagnosis and therapy of oral squamous cell carcinoma.Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathwayArtemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.The antiviral activities of artemisinin and artesunate.Amodiaquine pharmacogenetics.Recent advances in artemisinin production through heterologous expression.Role of oxidative stress in stem, cancer, and cancer stem cells.Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms.
P2860
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P2860
Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@ast
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@en
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@nl
type
label
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@ast
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@en
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@nl
prefLabel
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@ast
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@en
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@nl
P921
P3181
P1433
P1476
Molecular pharmacology and pha ...... ts derivatives in cancer cells
@en
P304
P3181
P356
10.2174/138945006776359412
P407
P577
2006-04-01T00:00:00Z