Positive cooperativity of the p97 AAA ATPase is critical for essential functions
about
Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 MutantsElements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motorMutations in the Human AAA+ Chaperone p97 and Related DiseasesAltered cofactor regulation with disease-associated p97/VCP mutationsControl of p97 function by cofactor bindingStructure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPaseA Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48.Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domainsComputer simulation of assembly and co-operativity of hexameric AAA ATPasesDynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission.Structural and functional deviations in disease-associated p97 mutants.Structure and function of the AAA+ ATPase p97/Cdc48p.Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy.Structure and Function of p97 and Pex1/6 Type II AAA+ Complexes.Thioflavin T as a fluorescence probe for monitoring RNA metabolism at molecular and cellular levels.An information theoretic framework reveals a tunable allosteric network in group II chaperonins.Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.Asymmetric processing of a substrate protein in sequential allosteric cycles of AAA+ nanomachines.
P2860
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P2860
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
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2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@ast
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@en
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@nl
type
label
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@ast
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@en
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@nl
prefLabel
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@ast
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@en
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@nl
P2093
P2860
P356
P1476
Positive cooperativity of the p97 AAA ATPase is critical for essential functions
@en
P2093
Kunitoshi Yamanaka
Masatoshi Esaki
Shingo Nishikori
Shinya Sugimoto
Teru Ogura
P2860
P304
P356
10.1074/JBC.M110.201400
P407
P577
2011-05-06T00:00:00Z